leproma


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leproma

 [lep-ro´mah]
a superficial granulomatous nodule, rich in bacilli, the characteristic lesion of lepromatous leprosy. adj., adj lepro´matous.

le·pro·ma

(lĕ-prō'mă),
A fairly well-circumscribed discrete focus of granulomatous inflammation, caused by Mycobacterium leprae, which consists chiefly of an accumulation of large mononuclear phagocytic cells in which the cytoplasm seems finely vacuolated (that is, foam cells); the foamlike character of the macrophages is related to the engulfing of numerous acid-fast organisms.
[G. lepros, scaly, + -oma, tumor]

le·pro·ma

(lĕ-prō'mă)
A discrete focus of granulomatous inflammation, caused by Mycobacterium leprae.
[G. lepros, scaly, + -oma, tumor]

leproma

The nodular skin manifestation of leprosy (HANSEN'S DISEASE).

le·pro·ma

(lĕ-prō'mă)
A discrete focus of granulomatous inflammation, caused by Mycobacterium leprae.
[G. lepros, scaly, + -oma, tumor]
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References in periodicals archive ?
The TlyA protein sequence was retrieved from the Leproma server and submitted to the Dense Alignment Surface (DAS) tool of the Expasy web server (http://www.expasy.org/ tools/) to get the trans-membrane domains of the protein.
leprae y sus aminoacidos deducidos Cepas sensibles a Tipo de secuencia la rifampicina Muestras estudiadas Nucleotidica CGG CTG TCG GCG CTG CGG CTG TTG GCG CTG Aminoacidica Arg Leu Ser Ala Leu Arg Leu Leu Ala Leu Posicion de la mutacion, segun diversos sistemas numeracion Telenti Honore Leproma (c) y col.
Hence, a final diagnosis of verrucous carcinoma of buccal mucosa and leproma of the tongue was confirmed.
Acid-fast bacilli were found in the sediment fraction of 16 (69.6%) out of the 23 leproma samples submitted to microscopic analysis and, out of these, 12 (52.2%) in the supernatant fraction.
[...] Son cuatro pulpos de magnitudes colosales tendiendo sus tentaculos en toda la extension de nuestra isla para aprisionar y sepultar en su seno toda la grandeza que en ella existe [...] Son cuatro fieras hambrientas de oro, de todas las miserias humanas y de todas las pestilencias inimaginables [sic] [...] Son cuatro fantasmas diabolicos que aparecen en nuestro ambiente, inquietando todo instante de solaz y de placer [...] Son cuatro lepromas [sic] inmensos carcomiendo y martirizando el cuerpo del paciente Job, cuatro lepromas destilando pus, sangre y fetidez [...] Son cuatro ortigas causticas y candentes...
Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy.13 Histoid lepromas are sudden eruptions of dome-shaped papules and nodules having characteristic epidermal grenz zone and dermal spindle-shaped histiocytes.13 Moreover, no acid fast bacilli are seen in slit skin smear in our case.
(30,31) La lepromina H (obtenida a partir de lepromas humanos) y la A (obtenida de lepromas de armadillos) se han usado para evaluar la respuesta inmune celular; en los pacientes LL se ven respuestas negativas.
As replication of bacteria continues, the face of the person develops folds and granulomatous thickenings called lepromas. Advanced cases of lepromatous leprosy may cause a loss of sensitivity that results in self-mutilation, secondary infections, and blindness.
En cuanto a la forma lepromatosa, aparecen en el cuerpo nodulos grandes y blandos, o bien tumores (lepromas).
El tipo mas contagioso es la lepra lepromatosa que se caracteriza por las manchas de la piel que evolucionan hacia nodulos llamados lepromas o leprones y que cubren el cuerpo, y que en la cara produce infiltraciones que la deforman denominandola facies leonina, agravada por la perdida del cartilago nasal.
(4) LL may present as a diffuse variant, in which there are no circumscribed elements, i.e., nodules (lepromas), macules, or plaques, but instead characterised by diffuse and massive infiltration of the skin, known as diffuse LL or Lucio-Latapi leprosy (5) which were found in this patient.