leontiasis


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leontiasis

 [le″on-ti´ah-sis]
the leonine facies (lionlike face) of a person with lepromatous leprosy, due to nodular invasion of the subcutaneous tissue.

le·on·ti·a·sis

(lē'on-tī'ă-sis),
The ridges and furrows on the forehead and cheeks of patients with advanced lepromatous leprosy, giving a leonine appearance.
Synonym(s): leonine facies
[G. leōn (leont-), lion]
A deeply furrowed ‘lumpy’ face with prominent superciliary arches, classically seen in lepromatous leprosy
DiffDx Hyperimmunoglobulin E syndrome, chronic granulomatous disease, van Buchem’s disease, leontiasis ossium—idiopathic leonine facies; features due to overgrowth of bones, as in Paget’s disease or McCune-Albright syndrome, polyostotic fibrous dysplasia or soft tissue, as in hypothyroidism with myxoedema of periorbital tissues, epidermoid carcinoma, Sézary syndrome, which is characterised by generalized exfoliative dermatitis, oedema, erythema, pachydermia, palmoplantar keratoderma

le·on·ti·a·sis

(lē'on-tī'ă-sis)
A lionlike appearance due to ridges and furrows on the forehead and cheeks of people with advanced lepromatous leprosy.
Synonym(s): leonine facies.
[G. leōn (leont-), lion]

leontiasis

The lion-like appearance of the face, featuring deep furrows and ridges, that occurs in some cases of advanced leprosy (HANSEN'S DISEASE).
References in periodicals archive ?
"It's a very, very rare condition and -- as this case is true classical leontiasis ossea -- it is even more rare," he explained.
(1,2) The term "leontiasis ossea" has been generalized to describe the appearance of craniofacial hypertrophy in the setting of many diseases--paget disease, fibrous dysplasia, reactive inflammatory bone disease, renal osteodystrophy--which result in leonine facies.
(3,6) The rarest pattern--and that most representative of an advanced disease state--is uremic leontiasis ossea which presents as marked expansion of the mandible and maxilla, occasionally with obliteration of the maxillary sinuses and splaying of the teeth.
Aretaeus the Cappadocian accurately described leprosy in the second century A.D., but he referred to it as leontiasis because of the facial deformity involved with the disease (leonis is Latin for lion, which described the bone abnormalities of people with the disease and is now used to describe the appearance of people with Paget's disease).
Craniofacial disease can manifest as headaches and facial distortion (leontiasis ossea).
Leontiasis ossea, slipped epiphyses and granulosa cell tumor of the testis with renal disease: report of a case with autopsy findings.