lentivirus

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lentivirus

 [len´tĭ-vi″rus]
any member of a genus of retroviruses that have long incubation periods and cause chronic, progressive, usually fatal diseases in humans and other animals. Species include the types of human immunodeficiency virus.

len·ti·vi·rus

(len'ti-vī'rŭs),
A genus in the family Retroviridae containing five serogroups that reflect the host with which they are associated. Among the primate lentiviruses are human immunodeficiency viruses types 1 and 2.

lentivirus

(lĕn′tĭ-vī′rəs)
n. pl. lentivi·ruses
Any of a group of retroviruses of the genus Lentivirus that cause diseases with a long latent period and a slow, progressive course. HIV is a lentivirus.
References in periodicals archive ?
Both goat and sheep lentiviruses have multiple clinical manifestations, including articular, neurological, respiratory, and mammary ones, in addition to progressive weight loss (BLACKLAWS, 2012; HASEGAWA et al., 2016).
At day 10 after infection of shSf3a1 or shSf3b1 lentiviruses on MGT-transduced ExCFs, the percentage of cells expressing cardiac marker, [alpha]MHC-GFP, or cTnT and positive cells dropped dramatically (Figure 2(a)).
The activity of Nef to counteract SERINC5 is essential for guaranteeing viral infectivity, which is highly conserved among primate lentiviruses, and correlates with the prevalence of these species.
The two closely related human lentiviruses HIV-1 and HIV-2 are responsible for the 21th century AIDS pandemic (Piot, et al, 2015; UNAIDS, 2013).
SiRNA lentivirus of G6PD gene, which included three target siRNA lentiviruses and a negative control siRNA lentivirus, was designed and synthesized by Shanghai Ji Kai Gene Technology Co., Ltd.
Transmission of small ruminant lentiviruses. Vet Microbiol 101: 199-208.
"We tried for a long time to introduce Cas9 with plasmids or lentiviruses, and then to express separately the single-guide RNA in the cell," Schumann said.
Key areas of concentration include: personalized medicine including diagnostics, proteomics, biomarkers, companion diagnostics and related systems; cancer vaccines; immune modulation; stem cells; gene therapy; angiogenesis modulation; signal transduction; and primate lentiviruses.
For cell infection, 30% confluent 5637 and T24 cells were incubated with lentiviruses for 48 h, and the medium, which contained puromycin (10 mg/mL; Sigma-Aldrich, USA), was replaced to select stable clones.
Now some scientists are attempting gene therapy using lentiviruses, modified versions of HIV, to deliver genes to patients' cells (SN: 8/10/13, p.
Then, the supernatants containing GFP (blank group), miR-155 (OE group), or miR-155 sponge (Sponge group) lentiviruses were collected and used to infect fibroblast cells.
As an example, lentiviruses (HIV-1) have evolved into new forms with a complex reverse transcription strategy including a strand displacement event controlled by the central polypurine tract (cPPT), which serves for plus-strand initiation and priming [3, 4].