Within caudate nucleus (H), TDP-43 pathology is present including an intranuclear lentiform
inclusion (black arrow); basal forebrain TDP-43 pathology was conspicuous (I).
papillae were located on the dorsal aspect of the lingua as reported in cow (Scala et al.) and the Jamunapari goat (Emura et al., 2011).
Three long lentiform
conglomerate interlayers are exposed in the middle part of the section.
Figure-3: Subtle increased signal in bilateral caudate and lentiform
nucleus (green arrow) and subcortical ribboning (red arrow) on DWI.
In sporadic Creutzfeldt-Jakob disease, there is an anterior predominance of basal ganglia MRI changes (i.e., caudate nucleus is more frequently and more severely involved than the lentiform
nucleus, whereas the thalamus is the least frequently and severely involved deep gray matter structure).
Using the WFU atlases and Talairach atlas labels, 21 nonoverlapping ROIs were selected: 11 level-2 ROIs (posterior lobe, anterior lobe, frontal-temporal space, limbic lobe, medulla, pons, midbrain, occipital lobe, temporal lobe, parietal lobe, and frontal lobe) and 10 level-3 ROIs (insula, extra-nuclear, lentiform
nucleus excluding putamen, claustrum, thalamus, fourth ventricle, third ventricle, lateral ventricle, caudate, and putamen).
She had CT brain showing calcification in basal ganglia involving caudate nucleus lentiform
nucleus and thalamus, in the centrum semi ovale bilaterally and also demonstrated subcortical dense curvilinear calcification bilaterally (Figure 1).
The radiologist identified a nonenhancing, hyperdense lentiform
mass within the left mesotympanum.
GHB enhances the release of the neurotransmitter acetylcholine in the striatal region of the brain (i.e., caudate nucleus & lentiform
There is frequent incomplete cleavage of the heads of the caudate nuclei and thalami, but the hypothalamus and lentiform
nuclei are well-separated.
FDGPET/CT showed a hypermetabolic lesion in the left temporal lobe and hypometabolism around the hypermetabolic mass lesion encroaching on thalamus, and lentiform
nucleus, probably due to the oedematous changes (Figure 2).