In our study, we found that in right frontal white matter, myoinositol levels are increased in bipolars relative to normals, and in the right lentiform
nucleus, NAA, glutamate+glutamine (the levels are so low these compounds are often considered together), and creatine are all decreased in bipolars relative to normals.
Early CT finding in cerebral infarction: Obscuration of the lentiform
Lacunar infarcts were seen in the right lentiform nucleus and thalamus and in the superficial white matter.
There was hyperintensity of the posterior left lentiform nucleus/posterior limb of the internal capsule and a small lacuna at the cortical-subcortical junction in the left hemisphere.
In the right frontal white matter, myo-inositol was significantly increased, and in the right lentiform
region, N-acetylaspartate, glutamate/glutamine, and creatine were significantly decreased in bipolar patients, compared with healthy normals, Dr.
The MRI imaging showed no differences between bipolar subjects and controls in total brain volume, cerebellar volume, lentiform
nucleus, corpus callosum area, cerebellar vermis area, or thalamic area.
Wilson's disease is characterized by the deposition of copper in the basal ganglia and thalami characterized by T2 hypointensity in the lentiform
nuclei and thalami.
Well-described acute ischemic findings on noncontrast head CT include a hyperdense middle cerebral artery (MCA) (1) parenchymal hypodensity within a vascular territory, loss of the gray-white matter junction including obscuration of the lentiform
nucleus (2) and loss of the insular ribbon, (3) and sulcal effacement (Figure 1).
Such signs include "blurring" of the gray matter-white matter junction due to decreased attenuation of the gray matter as manifested by the "insular ribbon" sign (loss of the usual slightly increased attenuation of the insular cortex just superficial to the external/extreme capsules [Figure 1]) or "obscuration" of the lentiform nucleus (loss of the normal attenuation difference of the globus pallidus and/or putamen with respect to contiguous white matter structures [Figure 2]).
8) Cytotoxic edema of gray matter is seen as increased T2 signal and, in the case of MCA ischemia, is often first identified in the region of the insular cortex (ie, the MR corollary of the "insular ribbon" sign on a CT scan) or involving the lentiform nuclei of the basal ganglia (ie, the MR corollary of "obscuration" of the lentiform nucleus on a CT scan).