Filgrastim XM02 (Tevagrastim[R]) after autologous stem cell transplantation compared to lenograstim
: favourable cost-efficacy analysis.
Welte, "G-CSF: filgrastim, lenograstim
and biosimilars," Expert Opinion on Biological Therapy, vol.
) recombined human granulocyte colony-stimulating factor involved in the production of granulocytes, macrophages, and megakaryocytes.
Use of glycosylated recombinant human G-CSF (lenograstim
) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia: final results of AML-13, a randomized phase-3 study.
Comparison of outcome of allogeneic bone marrow transplantation with and without granulocyte colony-stimulating factor (lenograstim
) donor-marrow priming in patients with chronic myelogenous leukemia.
Patients receiving gemcitabine plus docetaxel were assumed to receive treatment with lenograstim
to prevent neutropenic complications; those with prior pelvic irradiation were assumed to receive a 25% dose reduction of gemcitabine plus docetaxel .
prevents morbidity from intensive induction chemotherapy in the treatment of inflammatory breast cancer.
Synthetic G-CSF (granulocyte colony stimulating factor, e.g., filgrastim, lenograstim
) is also being prescribed to improve the corresponding neutropenia (a decrease of the neutrophil granulocyte count below 0.5x[10.sup.9]/L) in recent years (2).
Existing G-CSF products are marketed as Filgrastim (E.coli derived) and Lenograstim
On day 14 after admission, at the onset of pancytopenia, subcutaneous administration of recombinant human G-CSF (Lenograstim
; Chugai Pharmaceutical Co.