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a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Farlex Partner Medical Dictionary © Farlex 2012


n. pl. leiomyo·mas or leiomyo·mata (-mə-tə)
A benign tumor derived from smooth muscle, occurring most often in the uterus.

lei′o·my·o′ma·tous (-ō′mə-təs, -ŏm′ə-) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


Fibroma, plural, leiomyomata or, incorrect, but increasingly popular, leiomyomas A benign, well-circumscribed smooth muscle tumor most common in the uterus and stomach. See Fibroid, Fibroma, Intestinal leiomyoma.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


A benign tumour of smooth muscle found most commonly in the womb (uterus). Leiomyomas often contain much fibrous tissue. Also known as FIBROID, fibromyoma or leiomyofibroma.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


A benign tumor composed of muscle tissue. Leiomyomas in the uterus are sometimes called fibroids.
Mentioned in: Hysterosonography
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about leiomyoma

Q. uterine fibroids. Whats the best way to deal with them? My doctor says hysterectomy? What about my hormones?

A. Yes, drugs that suppress the levels of the female sex hormones (estrogen) are successful for treating uterine fibroids. However, the relief is only temporary and the fibroids recur once the treatment is stopped. In addition, these treatments cause side effects similar to menopause.

Surgery is the definitive treatment, especially for complications such as bleeding or pain, and when there's a suspicion for malignancy.

You may read more here: http://www.nlm.nih.gov/medlineplus/ency/article/000914.htm

More discussions about leiomyoma
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References in periodicals archive ?
A total of 150 uterine leiomyoma patients and an equal number of controls without any abnormal reproductive history were included in the present study.
Deep soft-tissue leiomyoma of the forearm mimicking a primary bone tumor of the ulna.
Leiomyomas represent only 1.3% of the soft tissue tumors in the head and neck and 0.16% of them occur in the auricle [2].
Multiple oral leiomyomas in an infant: a rare case.
Studies were included if they met the following criteria: 1) prognostic studies with observational (retrospective or prospective) or randomized research design, 2) evaluating ADC as a predictor factor for post-UAE change in uterine leiomyoma volume, diameter or size (at any follow-up time point), and 3) included women receiving UAE for the treatment of uterine leiomyomas.
Leiomyoma cutis: a clinicopathological series of 37 cases.
Cutaneous leiomyoma with cytologic atypia, akin to uterine symplastic leiomyoma.
Paraurethral Leiomyoma as an Incidental Finding in Patient with Fibroid Uterus.
Leiomyoma of the Round Ligament of the Uterus: Case report and review of literature.
Ultrasonographic, Surgical and Histopathological Findings of a Uterine Leiomyoma in a Cow.
Such rapid growth of uterine leiomyoma in early postpartum period has never been reported in the literature, only one case reported by Manyonda et al.7 A rapidly growing uterine fibroid postpartum, was done.