Two major types of situs ambiguous (SA) have been described: SA with polysplenia (also known as PS, left isomerism, or bilateral left-sidedness
) and SA with asplenia (also known as right isomerism or bilateral right-sidedness).
In all vertebrate embryonic studies to date, Nodal signaling pathway members of the nodal, lefty and pitx2 gene families are asymmetrically expressed on the left side of the embryo and are thought to convey left-sidedness
' to developing organs (Amack et al., 2007; Yost, 1999).
"He will bring something different to the team, a wee bit of pace in the wide left area and natural left-sidedness
which we have lacked."
study also showed an excess of left-sidedness
in the distribution of melanomas among 82,587 affected patients in the SEER registry.
Gregory Vignal's natural left-sidedness
has given Blues a better balance so far this season
, explosiveness, and anger led us to prescribe Lachesis (bushmaster snake).
Heterotaxia with polysplenia, also known as left isomerism or bilateral left-sidedness
, is characterized by a midline or ambiguous location of the majority of chest and abdominal viscera, multiple spleens, and an absence of some right-sided structures, such as the IVC.
The Dutch World Cup player's preferred position is centre-back but his left-sidedness
might be of interest to a manager short of left-backs.
Hodgson said: "He's a left-sided player and will bring experience, quality, left-sidedness
, his huge talent and a bit of ambition.