left shift


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Related to left shift: Right shift

left shift

Hematology An ↑ in a peripheral blood smear of immature granulocytes with ↓ nuclear segmentation, ie 'band' forms, due to ↑ production of myeloid cells in the BM, caused by acute infection Physiology An ↑ in Hb's affinity for O2–as represented by the oxygen dissociation curve, where the P50 is ↓ and shifted to the left, as occurs with ↑ pH–Bohr effect or ↓ temperature. Cf Right shift.

left shift

1. In hematology, an increase in the number of immature polymorphonuclear leukocytes in the circulating blood. See: Arneth's classification of neutrophils
2. In acid-base physiology, a left-shifted oxyhemoglobin dissociation level, indicating an increased affinity of hemoglobin for oxygen.
Synonym: shift to the left
See also: shift
References in periodicals archive ?
The right and left shift keys moved the cursor night and down, respectively.
Extra signs showed greater sensitivity and accuracy than left shift. However, specificity of extra sign and left shift were poor, 50% and 60%.
Other causes of left shift can include severe inflammatory disease, myelodysplastic syndromes, myeloproliferative disease, chronic myeloid leukemia, myelofibrosis, metastatic bone marrow malignancy, and acute organ transplant rejection.
On a recheck CBC, the PCV value had improved but the leukocytosis was more severe despite improvement in the left shift (Table 1).
(3) Laboratory tests generally show leukocytosis with a left shift, as well as negative blood, CSF, and urine cultures.
The 5 WBC-specific flags with user-definable thresholds that we used as our model system are called (1) blasts, (2) immature granulocytes, (3) left shift, (4) atypical lymphocytes, and (5) abnormal lymphocytes/lymphoblasts flags.
A massive left shift gave the lead to the teams who had chosen the left in the first beat, whilst the second beat heavily favoured those who went to the right.
Laboratory data showed normal hemoglobin level, thrombocytosis--1357 x [10.sup.9] /1, left shift in the differential blood count with 8% myeloblasts and 4% erythroblasts.
Advocates of the pH-stat method argue that since hemoglobin's affinity for oxygen increases as temperature decreases the addition of CO2 or decrease in ventilation (resulting in a respiratory acidosis) during this method will counter the left shift and therefore oxygen release at the tissues will be improved.
Laboratory results show leukocytosis with a left shift. Diagnosis can be confirmed by challenge, and elimination of the offending agent usually results in resolution of symptoms within 72 hours.
Hemogram revealed neutrophilia with left shift where band neutrophils (0.53 x[10.sup.9]/L; reference range <0.3 x[10.sup.9]/L) with segmented neutrophils (13.45 x[10.sup.9]/L; reference range 2.5-12.5 x [10.sup.9]/L) were elevated.
It is accepted that according to the Alvarado Scoring System which consists of right lower quadrant tenderness, rebound tenderness, migrating pain, nausea and/or vomiting, anorexia, fever, leucocytosis and a left shift in the leukocyte count.