lectins


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lectins

A group of proteins that bind firmly to specific small sugar (oligosaccharide) parts of glycoproteins and glycolipids. Most lectins in humans are cell membrane proteins with binding sites on the outside of the membranes, and are concerned in cell migration, tissue formation, fertilization, phagocytosis, agglutination, etc.
References in periodicals archive ?
To compare the glycopatterns of urinary protein between the NDRD groups, 10 and 8 lectins were detected as effective binding signals in the MN and IgAN groups, respectively.
Lectins are just one of a whole group of compounds that act as a defense system against invaders.
Lectins are a type of protein found in many foods including grains and beans.
England's Dr Tom Greenfield examined the effects of lectins on different blood types and said that the protein can 'absolutely' play a role in brain disorders.
The lectins tested and their glycan-binding specificities are shown in Table 2.
Both PVA-GA-Con A and PVA-GA-PpeG proved to be promising and attractive due to the low cost affinity chromatography supports for glucose/mannose-bearing glycoconjugates and glucose/mannose-specific lectins, respectively.
These lectin molecules can recognise the amount of sugar units and the differences in sugar units can be responsible for the changes during disease in the body.
Lectins are a group of proteins (or glycoproteins) of non-immune origin that bind specifically and reversibly to carbohydrates, resulting in cell agglutination and precipitation (Goldstein et al.
Lectins can recognize specific carbohydrat e moieties thereby controlling various cellular functions as serum glycoprotein turnover, cell-to-cell, host and pathogen interactions and a number of innate immune responses (Ehsan and Altaf, 2009).
Furthermore, we conducted sugar-blocking experiments using commercial lectins to investigate the role of sugar compound structures in the OSE on larval settlement, and to determine whether the "larval lectin receptor model" (Kirchman et al 1982, Matsumura et al.