lead compound


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lead compound

A peptide, small molecule, or other agent with pharmacological or biochemical properties which suggest that it may have therapeutic potential and value as a starting point for drug development.
References in periodicals archive ?
In pharmaceuticals, lead compound obviousness analysis usually involves analyzing the substitution of a portion of a structurally similar known compound to arrive at the claimed compound.
The company's lead compound, ThGRF, is an analogue of a natural hormone known as growth hormone releasing factor.
The old reporting threshold required facilities to report lead and lead compound emissions to air, water and land if they annually manufactured or processed more than 25,000 pounds (55,000 kilograms).
If, however, a lead compound with radiolead added is stirred in water so that a tiny fraction of the molecules dissolve, that same tiny fraction of the molecules containing radio-lead also dissolves.
To gain marketing approval for our lead compound DAVANAT([R]) would be a major milestone in the development of our technology.
Carna Biosciences will handle compound screening and construct a protein expression system and CrystalGenomics will analyze the structure of Cdc7-ASK and optimize a lead compound.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under a SPA and Fast Track, acts together with chemotherapy as a chemoprotectant and an immunomodulator.
To gain FDA marketing approval for our lead compound DAVANAT([R]) would be a major milestone in the development of our technology.
Othera's lead compound, OT-551, an eye drop, is being developed to treat several major eye diseases and conditions, including the dry and wet forms of age-related macular degeneration (AMD), cataracts, ocular allergy and dry eye syndrome.
The lead compound has been identified from a portfolio of numerous viable compounds.