lazy leukocyte syndrome

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lazy leukocyte syndrome

a syndrome occurring in children, marked by recurrent low-grade infections, associated with a defect in neutrophil chemotaxis and deficient random mobility of neutrophils.

An idiopathic condition due to defective neutrophil chemotaxis after appropriate stimuli—e.g., endotoxin or epinephrine—and inefficient egress of neutrophils from the BM
Prognosis Uncertain

lazy leukocyte syndrome

An idiopathic condition due to defective PMN chemotaxis after appropriate stimuli–eg, endotoxin or epinephrine and inefficient egress of PMNs from the BM Clinical ↑ Pyogenic infections–eg, gingivitis, abscess formation, pneumonia, neutropenia Prognosis Uncertain

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