latrotoxin


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α-latrotoxin

A neurotoxin produced by the black widow spider–Lactrodectus mactans, which causes synaptic vesicle exocytosis and the release of neurotransmitters from presynaptic nerve terminals, acting with synaptotagmin, a synaptic vesicle-specific membrane protein. See Black widow spider, Synaptotagmin.
References in periodicals archive ?
Their venom contains a neurotoxin called latrotoxin, which can cause nausea, vomiting, headache, fatigue, muscle spasms and localised paralysis.
Vesicle exo-cytosis stimulated by alpha- latrotoxin is mediated by latrophilin and requires both external and stored Ca2+.
a- Latrotoxin receptor CIRL/Latrophilin-1 (Cl-) defined an unusual family of ubiquitous G-protien-linked receptors.
Cloning and structure of a-latroinsectotoxin, and novel insect-specific member of the latrotoxin family: functional expression requires C-terminal truncation.
They inject a venom called latrotoxin, which can result in nausea, vomiting, headache, fatigue, muscle spasms and paralysis.
They inject venom called latrotoxin, which results in nausea, vomiting, headache, fatigue, muscle spasms and patchy localised paralysis.
They are considered highly dangerous as they inject neurotic venom called latrotoxin, which results in the condition latrodectism.
The black widow spider is considered highly dangerous as it injects neurotic venom called latrotoxin through its bite, which results in the condition latrodectism.