latex agglutination test
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Related to latex agglutination test: precipitation test
latex[la´teks] (L. “fluid”)
1. any of various white viscid fluids secreted by certain plants; the variety from Hevea brasiliensis, the rubber tree, was formerly the main source of commercial rubber. Allergic reactions to natural latex are an important cause of type IV hypersensitivity reactions. See also latex allergy.
2. any of several synthetic fluids resembling natural latex, including polystyrene and polyvinyl chloride; these are not causes of latex allergy.
latex agglutination test (latex fixation test) a diagnostic study used to detect certain antibodies in body fluids; latex particles are used as passive carriers, and particles clump together following the addition of the antibody. One use is as a serologic test for rheumatoid factor in diagnosis of rheumatoid arthritis.
la·tex ag·glu·ti·na·tion test
a passive agglutination test in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen.
Synonym(s): latex fixation test
latex agglutination testLatex fixation test Lab medicine An assay that uses visible agglutination as an end-point, to detect a reaction between derivatized particles and an analyte
aggregation of separate particles into clumps or masses; especially the clumping of bacteria or blood cells by antibody specific to, or directed against, surface antigenic determinants. See also agglutinin.
bacterial agglutination test
a diagnostic procedure that employs serum or other body fluid of unknown antibody titer, titrated with standard suspension of bacteria as antigen. These may be performed quantitatively in 96-well microtitration plates or qualitatively on slides.
the agglutination of particulate antigen by an antibody raised against a different but related antigen; see also group agglutination (below).
agglutination—usually to a lower titer—of various members of a group of biologically related organisms by an agglutinating antibody made to one of that group.
clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell agglutination.
latex agglutination test
see passive agglutination test (below).
microscopic agglutination test
one in which the test mixtures are examined microscopically to detect the agglutination.
mucus agglutination test
see mucus agglutination test.
passive agglutination test
an agglutination reaction in which a soluble antigen, such as gonadotropin, is linked to inert particles such as latex beads or tanned erythrocytes.
the clumping together of platelets owing to the action of platelet agglutinins. Such agglutinins are important in platelet typing.
slide agglutination test
a rapid screening or semiquantitative test in which antibody and antigen are mixed on a glass slide and observed for agglutination.
see bacterial agglutination test (above).
tube agglutination test
an agglutination test for the identification of bacteria carried out in a test tube, a positive reaction consisting of a clearing of a prior opalescence.