late syphilis


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Related to late syphilis: latent syphilis, Sifilis

late syph·i·lis

involvement of the cardiovascular or central nervous system, or the development of a gumma in any organ, due to infection with Treponema pallidum; usually occurs several years to 2-3 decades after the initial infection.
Synonym(s): tertiary syphilis
References in periodicals archive ?
A systematic review [54] of penicillin and nonpenicillin regimens for syphilis included 11 RCTs, but the authors reported that the "evidence defining treatment for late syphilis or HIV-infected persons is limited."
This may be because the TPHA test is relatively insensitive in the early primary stage of syphilis; 8 sera were non-reactive to both VDRL and RPR, but TPHA reactive because those 8 cases were treated cases of early and late syphilis. One serum sample was only VDRL reactive, due to biological false positive reaction.
Tertiary syphilis (late syphilis) is not mandatory.
Forms 2003 2004 2005 2006 2007 2008 Early syphilis 36.5 24.5 18.5 17.3 14.2 12.1 (primary, secondary) Early latent 54.7 53.9 41.9 35.5 31.5 28.6 syphilis Late syphilis 0.07 0.2 0.1 0.1 0.2 0.1 Other 0.4 0.3 0.2 0.1 -- -- unspecified forms All forms 92.1 79.3 60.9 53.2 46.0 40.9 Forms 2009 2010 2011 2012 2013 Early syphilis 11.7 9.8 10.4 12.5 13.9 (primary, secondary) Early latent 26.9 24.6 22.0 23.7 21.6 syphilis Late syphilis 0.2 0.1 0.1 0.1 0.1 Other -- -- -- -- -- unspecified forms All forms 40 34.5 33.0 36.6 35.6 Figure 2: Dynamics of the incidence of STIs in the RoK for the period between 2003 and 2013, number of cases.
Although these tests are widely available and relatively inexpensive, they are limited by their lack of sensitivity in early and late syphilis and by false-positive reactions1-3.
"This treatment is typical for late syphilis and not the early syphilis that this case was," Dr.