laser capture microdissection


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laser capture microdissection

The collection of selected cell groups from tissue sections for analysis, e.g., of morphological or genetic characteristics.
See also: microdissection
References in periodicals archive ?
Arcturus is the leading company in Laser Capture Microdissection and reagent systems for the analysis of microscopic tissue samples, with systems installed in leading cancer centers and other research and clinical laboratories worldwide.
The global laser capture microdissection market is expected to USD 124.97 million by 2020 from USD 72.45 million in 2015, at a CAGR of 11.52% between 2015 and 2020.
KRAS mutations were identified in 12 pretreatment specimens, but only 9 posttreatment specimens, despite using laser capture microdissection to increase the proportion of tumor tissues and allele-specific PCR to improve the sensitivity of assays in the latter samples.
Expression profiling of ductal carcinoma in situ by laser capture microdissection and highdensity oligonucleotide arrays.
In addition to complete revision of the existing material, several new chapters have been added to the second edition on bioinformatics; microarrays; methylation assays; FISH; laser capture microdissection; quality assurance; chimerism studies for bone marrow transplantation; and the ethical, legal, and social issues of genetic counseling.
(26-33) Some studies have used laser capture microdissection (LCM) to enrich disease-specific material and enhance the probability of discovering biomarkers.
Arcturus introduced the PixCell lle Laser Capture Microdissection System ...
Percentages of laboratories using manual microdissection, laser capture microdissection, or no microdissection by survey period.
(5.) Emmert-Buck MR, Bonner RF, Smith PD, Chuaqui RF, Zhuang Z, Goldstein SR, et al Laser capture microdissection. Science 1996;274:998-1001.
The technique of CGH can be optimized, however, using array CGH and laser capture microdissection to ensure pure cell populations for analysis.