In the current study, HPV-11 was detected mostly in positive laryngeal papillomas (100%) which are in concordance with the other studies (28, 29).
Human papillomavirus 6, 11, and 16 in laryngeal papillomas. J Pathol 1991; 165(3):243-246.
(1) Laryngeal papillomas, single or in clusters, are found mainly on the vocal folds, but can affect other areas of the larynx.
Management of laryngeal papillomas commonly involves surgery, adjuvant therapy to eliminate viral replication, and vaccines.
It appears that intralesional injections of cidofovir have the potential to be an important adjunct to the treatment of laryngeal papilloma. With further refinement of the dosage and frequency schedules, it could in time become a principal therapy for this disease.
This is a preliminary report of an ongoing study to test the efficacy of intralesional injections of the antiviral drug cidofovir in adults with recurrent laryngeal papillomas in whom multiple other treatments have previously failed.
Laryngeal papillomas, which were originally described in the 17th century as "warts in the throat," occur in two age groups: adults and young children.
Laryngeal papillomas are caused by an infection with human papillomavirus (HPV).
The drug's efficacy has also been suggested in the treatment of esophageal papillomas, as reported in one patient by Van Cutsem et al,  and in the treatment of laryngeal papillomas in children and adults, as reported by Snoeck et al.