The senior author (R.T.S.) has described a case ofbilateral granuloma and varicosity in the midportion of the vocal folds, as well as a
laryngeal granuloma of the false vocal fold.
It is important to understand the meaning of the term "laryngeal granuloma" and the general implications of this disease process on the voice.
Causes of laryngeal granuloma formation include traumatic intubation, surgery, voice abuse, and laryngopharyngeal reflux.
Botulinum toxin as adjunctive therapy in refrac-tory
laryngeal granuloma. J Laryngol Otol.
An effective management regimen for
laryngeal granuloma caused by gastro-esophageal reflux: combination therapy with suggestions for lifestyle modifications.
Laryngeal granuloma as a complication of the CO2 laser.
(2) If a
laryngeal granuloma fails to respond to aggressive medical therapy, laryngoscopy with biopsy is indicated to confirm the diagnosis.
Laryngeal granuloma secondary to gastro-esophageal reflux.
Laryngeal granuloma is frequent (see below), and extrusion and mucosal ulceration are possible.
Botulinum toxin: Helpful adjunct to early resolution of
laryngeal granulomas. J Laryngol Otol 2004; 118(10):781-5.
We recently reported our initial experience with PDL in the treatment of
laryngeal granulomas in 10 patients who failed to respond to traditional management, including voice therapy and aggressive antireflux therapy.
The etiology of
laryngeal granulomas is multifactorial, but LPR should always be suspected as possibly playing a role.