The senior author (R.T.S.) has described a case ofbilateral granuloma and varicosity in the midportion of the vocal folds, as well as a laryngeal granuloma
of the false vocal fold.
It is important to understand the meaning of the term "laryngeal granuloma" and the general implications of this disease process on the voice.
Causes of laryngeal granuloma formation include traumatic intubation, surgery, voice abuse, and laryngopharyngeal reflux.
Botulinum toxin as adjunctive therapy in refrac-tory laryngeal granuloma
. J Laryngol Otol.
An effective management regimen for laryngeal granuloma
caused by gastro-esophageal reflux: combination therapy with suggestions for lifestyle modifications.
as a complication of the CO2 laser.
(2) If a laryngeal granuloma
fails to respond to aggressive medical therapy, laryngoscopy with biopsy is indicated to confirm the diagnosis.
secondary to gastro-esophageal reflux.
is frequent (see below), and extrusion and mucosal ulceration are possible.
Botulinum toxin: Helpful adjunct to early resolution of laryngeal granulomas
. J Laryngol Otol 2004; 118(10):781-5.
We recently reported our initial experience with PDL in the treatment of laryngeal granulomas
in 10 patients who failed to respond to traditional management, including voice therapy and aggressive antireflux therapy.
The etiology of laryngeal granulomas
is multifactorial, but LPR should always be suspected as possibly playing a role.