In the tropical regions
lapacho has proved to be highly effective in controlling such scourges as schistosomiasis -- a riverborn parasite -- which is estimated to afflict 300 million people and Chagas' disease, better known as 'sleeping sickness', which is transmitted by the tetse fly.
The species included exotics such as Eucalyptus grandis, Eucalyptus camaldulensis, Melia azedarach (Paraiso gigante) and natives Cordia trichotoma (Peterevy), Tabebuia impetiginosa (
Lapacho), Cedrela fissilis (Cedro) among others (PMRN 2011:108).
13-Lapachone (3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione) and its isomer, u-lapachone are natural naphthoquinones extracted from the bark of the
Lapacho tree (Tabebuia avellanedae) or synthesized from lapachol or lomatiol.
[beta]-Lapachone treatment, a natural substance from the bark of the
lapacho tree, significantly reduced the expression of IL-12 family cytokines in microglia and thereby suppressed clinical severity [91].
Segun la distribucion potencial actual, tras eliminar las areas deforestadas y teniendo en cuenta la presencia de areas protegidas que garantizan un menor grado de perturbacion humana, las zonas mas recomendables para encontrar nuevas localidades de esta especie serian el centro-sur del Parque Nacional (PN) Iguazu, el oeste del Parque Provincial (PP) Urugua-i y las Reservas Privadas (RP) Tomo, Itacuarahy y
Lapacho Cue (Figs.
It has been collected from 15 host plants, Avena sativa (cultivated oat), Saccharum officinalis (sugarcane), Sorghum halepense (Johnson grass), Zea mays (corn), Tritricum aestivun (wheat), Bromus unioloides (rescuegrass) (Poaceae), Dahlia pinnata (dahlia) (Asteraceae), Tabebuia
lapacho (yellow palmer trumpettree) (Bignoniaceae), Ipomaea sp.