laminin 5


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Related to laminin 5: LAMA5

laminin 5

A complex glycoprotein composed of three subunits (alpha, beta and gamma), which is involved in:
• Cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes;
• Signal transduction via tyrosine phosphorylation of pp125-FAK and p80; and
• Keratinocytes differentiation.
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References in periodicals archive ?
Immunokimyasal tetkiklerle SP'de saptanmis olan baslica antijenler laminin 5, BP180 ve [beta]4 intergrin subunitesidir.
Otoantikorlarla baglanma sonrasi tip VII kollajen molekulunun dimer yapisinin engellendigi veya laminin 5 ve fibronektin gibi ligandlariyla iliskisinin bozuldugu dusunulmektedir (1).
The etiopathogenesis of autoimmune bullous diseases/Otoimmun bulloz hastaliklarin etyopatogenezi
The importance of laminin 5 in the dermal-epidermal basement membrane.
Effect of polysaccharides from Opuntia ficus-indica (L.) cladodes on the healing of dermal wounds in the rat
Anti-basement membrane autoantibodies in patients with anti-epiligrin cicatricial pemphigoid bind the alpha subunit of laminin 5.
Cicatricial pemphigoid: Report of five cases. (Original Article)
Genel bilgilerde bahsedildigi gibi otoimmun bulloz hastaliklarin immunopatogenezinin arastirilmasi amaciyla (ornegin envoplakin, periplakin, kollajen VII, laminin 5, vb.
ELISA for the diagnosis of autoimmune bullous disorders/Otoimmun bulloz hastaliklarin tanisinda ELISA

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