LAMB1

(redirected from laminin, beta 1)

LAMB1

A gene on chromosome 7q22 that encodes laminin beta 1, an extracellular matrix protein expressed in most tissues that produce basement membranes, and which is one of the 3 chains constituting laminin 1.
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The researchers also found highly suggestive associations between ulcerative colitis and genetic markers on chromosome 7q31 within or near the laminin, beta 1 (LAMB1) gene, which is a member of a gene family known to play a role in intestinal health and disease, and confirmed previously identified associations between ulcerative colitis and genetic variants in the interleukin 23 receptor (IL23R) gene on chromosome 1p31 and the major histocompatibility complex on chromosome 6p21.
Genetic markers associated with ulcerative colitis risk identified
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