LMNB2

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LMNB2

A gene on chromosome 19p13.3 that encodes lamin B2, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.
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References in periodicals archive ?
Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development.
Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons.