lambda light chain


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lambda light chain

one of two kinds of smaller polypeptide chains present in an immunoglobulin molecule. See also kappa light chain.
References in periodicals archive ?
Interpretation In summary, the patient has a mild plasmacytosis on the biopsy (~5-10%) that is lambda light chain restricted.
GE Healthcare's new resin, LambdaFabSelect, is a designed tool for the GMP-regulated purification of antibodies and antibody fragments that contain a lambda light chain.
Crescendo has already made use of its ability to knock out lambda light chain to generate proprietary 'triple knockout' mice that have the immunoglobulin heavy chain, kappa light chain and lambda light chain loci all functionally deleted.
Subsequent renal biopsy also showed lambda light chain amyloid.
Metachronous development of nonamyloidotic lambda light chain deposition disease and IgG heavy chain amyloidosis in the same patient.
Introduction of the complete lambda light chain locus, containing 30 functional V genes, by Abgenix scientists extends the earlier achievement of Dr.
Flow cytometric analysis of kappa and lambda light chain expression in evaluation of specimens for B-cell neoplasia.
Assessment of cerebrospinal fluid immunoglobulin patterns after isoelectric focusing: use of kappa and lambda light chain immunoperoxidase staining.
Antibodies with human heavy and lambda light chains are created by means of Kymouse HL strain while Kymouse HK produces antibodies with human heavy and kappa light chains.
The Kymouse HL strain produces antibodies with human heavy and lambda light chains whereas Kymouse HK generates antibodies with human heavy and kappa light chains.
The tumor cells were negative for CD20 (figure 3, A), positive for kappa light chains (figure 3, B), and slightly positive for both lambda light chains (figure 3, C) and CD38.
They are characterized by a broad diffuse band with one or more heavy chains and kappa and lambda light chains.