lagging strand

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Related to lagging strand: DNA replication

lagging strand

In DNA replication, the single strand forming a duplex in the direction away from the fork in the parental DNA. Replication on the lagging strand is discontinuous and can occur briefly in both directions.

lagging strand

the strand in DNA replication that is synthesized discontinuously, to generate Okazaki fragments (named after R. Okazaki who first detected them). These are later sealed by DNA LIGASE. See DNA, SEMICONSERVATIVE REPLICATION MODEL.

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References in periodicals archive ?

But on the lagging strand, as the name vaguely suggests, the new DNA can only be built in the opposite direction.

Scientists Watch DNA Copy And Paste Itself For The First Time

We will determine locus specific differences in the spread of maternal nucleosomes after replication, the effects of leading and lagging strand replication on nucleosome positioning and maternal nucleosome distribution, the renewal dynamics of posttranslational histone marks and chromatin binding proteins, and the kinetics of chromatin footprint re-establishment and gene (re)activation.

NChIP: Chromatin dynamics during DNA replication

Short sections of DNA produced from the replication of the lagging strand of DNA.