lagging strand
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Related to lagging strand: DNA replication
lagging strand
In DNA replication, the single strand forming a duplex in the direction away from the fork in the parental DNA. Replication on the lagging strand is discontinuous and can occur briefly in both directions.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
lagging strand
the strand in DNA replication that is synthesized discontinuously, to generate Okazaki fragments (named after R. Okazaki who first detected them). These are later sealed by DNA LIGASE. See DNA, SEMICONSERVATIVE REPLICATION MODEL.Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005