lactic acid dehydrogenase
Also found in: Dictionary, Acronyms, Encyclopedia.
Related to lactic acid dehydrogenase: lactate dehydrogenase test
lac·tate de·hy·dro·gen·ase (LDH),
name for a number of enzymes, including: l-lactate dehydrogenase (cytochrome), d-lactate dehydrogenase (cytochrome), l-lactate dehydrogenase, and d-lactate dehydrogenase. The first two enzymes transfer hydrogen to ferricytochrome c or to cytochrome b2, the last two transfer it to NAD+, in catalyzing the oxidation of lactate to pyruvate; the isozyme distribution of heart and muscle lactate dehydrogenase is of significant use in cases of myocardial infarction; a deficiency of a subunit will result in myoglobinuria after intense exercise.
Synonym(s): lactic acid dehydrogenase
lactic acid dehydrogenaseLactate dehydrogenase, a name for four enzymes:
(1) l-Lactate dehydrogenase (cytochrome), EC 18.104.22.168;
(2) d-Lactate dehydrogenase (cytochrome), EC 22.214.171.124;
(3) l-Lactate dehydrogenase, EC 126.96.36.199; and
(4) d-Lactate dehydrogenase, EC 188.8.131.52;