The drug inhibits the Rho kinase ROCK, a set of molecules that hold the puppet strings for the lacteals
Oral insulin from enterocele cells is transported to the lymphatic ducts (called lacteals
) in the center of the villi situated next to the blood vessels, then delivered to systemic circulation, in which it acts like subcutaneous injected insulin.
A description of the lacteals
, lymphatic fluid, the ovaries and at least part of the uterine tubes, flowed too from his keen observations.
Since it is mainly long chain fatty acids that are absorbed from the intestines via lacteals
and enter the central circulation at the thoracic duct (Shils, Olson, & Shike, 1994), enteral intake of long chain fats must be severely limited.
The term chylothorax is used to describe this fluid because the fluid resembles the appearance of chyle, which is the milky fluid taken up by the lacteals
from the intestines during digestion.
In human physiology Prout identified four stages in the formation of blood: digestion in the stomach, chymification in the duodenum, chylification in the lacteals
, and sanguification proper in the blood vessels.
The histology of the gut in these patients ranged from`mild hyperaemia and slight dilatation of the capillary and lymphatic vessels'  to`dilatation of the lacteals
of the villi' .