dehydrogenase

(redirected from lactate dehydrogenase (LDH), lactic acid dehydrogenase)
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dehydrogenase

 [de-hi´dro-jen-ās″]
an enzyme that mobilizes the hydrogen of a substrate so that it can pass to a hydrogen acceptor.
glucose-6-phosphate dehydrogenase an enzyme necessary for the oxidation of glucose-6-phosphate, an intermediate in carbohydrate metabolism. Hereditary deficiency of this enzyme in the erythrocytes is associated with a tendency toward hemolysis upon ingestion of certain antimalarial agents and sulfonamide drugs and fava beans (see favism.
lactate dehydrogenase (LDH) an enzyme that catalyzes the interconversion of lactate and pyruvate. It is widespread in tissues and is particularly abundant in kidney, skeletal muscle, liver, and myocardium. It appears in elevated concentrations when these tissues are injured.

de·hy·dro·gen·ase

(dē-hī'drō-jen-ās),
Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors), which are thus reduced; most of the oxidative enzymes (oxidoreductases, EC class 1) perform their oxidations in this manner.

dehydrogenase

(dē′hī-drŏj′ə-nās′, -nāz′, dē-hī′drə-jə-)
n.
An enzyme that catalyzes the removal of hydrogen from a substrate and the transfer of the hydrogen to an acceptor in an oxidation-reduction reaction.

de·hy·dro·gen·ase

(dēhī-drojĕ-nās)
Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors).

dehydrogenase

an enzyme, such as any of the respiratory enzymes, that catalyses a reaction in which hydrogen is removed from a molecule (often to be taken up by the ELECTRON TRANSPORT SYSTEM). For example, in the KREBS CYCLE the conversion of succinic acid (succinate) to fumaric acid (fumarate) is catalysed by succinate dehydrogenase, the hydrogen released being passed on to FAD.

de·hy·dro·gen·ase

(dēhī-drojĕ-nās)
Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors).