The IMPROVE trial was designed to address a knowledge gap: comparing the efficacy and safety of vaginal misoprostol versus buccal misoprostol for cervical ripening in women undergoing labor induction
Mifepristone vs balloon catheter for labor induction
in previous cesarean: a randomized controlled trial.
Oral misoprostol or vaginal dinoprostone for labor induction
: a randomized controlled trial.
and the risk of a cesarean delivery among nulliparous women at term.
Previously, different types of medical preparations such as vaginal prostaglandin E2 (Minprostin[R], a vaginal gel, Pfizer, NY, USA, or Propess, an insert with slow-release of PGE2, Ferring, Malmo, Sweden) or mechanical methods (balloon catheters, Bard[R]/Rusch[R], Cook Medical, USA) were used at the clinic as primary methods for labor induction
in the case of an immature cervix (Bishop score (BS) [less than or equal to] 5).
(11-13) In 2002, the first report on the sublingual administration of misoprostol for labor induction
[sup] Some women choose elective cesarean sections just because they are worried about an unsuccessful labor induction
It has been seen that induction with higher dose oxytocin increments does not shorten time to delivery, but is often associated with an increase in uterine hyperstimulation, whereas low dose oxytocin is found to be appropriate and safe for labor induction
Evidence on labor induction
suggests similar patterns.
A randomized comparison between misoprostol and dinoprostone for cervical ripening and labor induction
in patient with unfavorable cervices.
In another case, a woman with severe pregnancy complications was repeatedly denied labor induction
and a cesarean section until a 36-hour labor put the child in distress.
Increasing rates of labor induction
. Obstet Gynecol 2001;97(4 Suppl 1):S34.