labeling index


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labeling index

The rate at which cells take up identifiable chemicals that they use in cell division. The index is a measure of the rate of the reproduction of the cells, as in fetal tissue development or the growth of cancers.
See also: index
References in periodicals archive ?
Comparison of Immunophenotype and Cytokeratin (CK) 7, CK20, CDX-2, and Ki-67 Labeling Index (KLI) in Sinonasal Adenocarcinoma (SNAC) * P Value Stain SNAC REAH ([dagger]) IP CK7 9/10 (90) 16/16000) .
Overall, the best general markers of rodent liver cancer are increases in relative liver weight and cellular labeling index (particularly for the mouse) and liver hypertrophy.
Although a larger number of samples must be studied, the demonstrated correlation between the Ki-67 labeling index in tumor material and the Ki-67 RNA copy number in total urine offers the prospect of transferring the prognostic potential of the Ki-67 labeling index to the noninvasive diagnostic tool of RNA quantification in urine.
The tumor in this report demonstrated a similar degree of MIB-1 immunoreactivity, with a labeling index of 1.
Coumestrol exposure led to a significant increase in the labeling index of the uterine epithelium and the glands and stroma of the endometrium in all three groups of females (Table 3, Figure 3).
00001 NS (*) NS indicates not significant; KPS, Karnofsky performance score; PCV, procarbazine, lomustine, and vincristine; and LI, labeling index.
The strong correlation of ATM loss with the GCB subtype, low Ki-67 labeling index, and low Bcl-2 expression suggests that ATM protein might be more strongly correlated to PCNS DLBCL lymphomagenesis than non-CNS DLBCL, particularly in germinal center subtypes demonstrating low Ki-67 labeling indexes and low Bcl-2 expressions.
Labeling index (%) was calculated as the number of PCNA-positive cells expressed as a percentage of the total number of cells, and cell density (%) was determined as the proportion of stained cells per area.