This technique is extremely sensitive, the researchers say, allowing measurement of minute amounts of any labeled compound
Using a radioactively labeled compound
that binds to the active form of the primary glutamate receptor, the investigators analyzed brains slices from mice at different times after each had received a traumatic blow to the head.
These peaks clearly resolve in the TOF-SIMS mass spectrum, which confirms the presence of the labeled compound
Inclusion of an excess (2 mM) of unlabeled histamine in the incubation medium blocked the uptake of labeled compound
2]]urea calibrator solution was prepared by dissolving ~48 mg of the labeled compound
in 15 mL of 900 mL/L water-100 mL/L methanol.
National contract notice: a set of devices for the measurement of radioactively labeled compounds
Sekisui Medical also undertakes custom synthesis of labeled compounds
and evaluation tests related to pharmacokinetics through its ADME and Tox Research business.
OctreoPharm is focused on the development of radioactive labeled compounds
for molecular imaging diagnostics and therapeutic applications.
The concluding chapters discuss applications, including use of radiation and radioactive tracers in medicine, research uses of labeled compounds
and particle accelerators, and nuclear power.
The March Group currently represents a leader in providing custom synthesized isotope labeled compounds
including intermediates, final drug substances, and isotopically labeled biological standards.