The immediate precursor of ascorbic acid in those animals capable of ascorbic acid biosynthesis.
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Data also showed that birds injected with synthetic ACTH had lower levels of GLO (L-gulonolactone oxidase) activity in their kidneys, implying that low levels of stress are capable of down-regulating ascorbic acid biosynthesis in the chicken.
The objective of this study was to see if supplementation lowered the activity of the enzyme which catalyzes the synthesis of ascorbic acid in the glucose/xylose cycle, L-gulonolactone oxidase (EC; L-gulono-[gamma]-lactone:oxidoreductase GLO).