knockout

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knock·out

, knock-out (nok'out, nok'-out),
A genetically engineered organism in which the genome has been altered by site-directed recombination so that a gene is deleted.
Farlex Partner Medical Dictionary © Farlex 2012

knockout

(nŏk′out′)
adj. also knock-out (nŏk′out′)
Genetics Having a specific single gene inactivated or removed by genetic manipulation: knockout mice used in an experiment.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Experimental biology A genetically engineered mutant animal—e.g., Drosophila, mouse, fish, et al—in which a targeted gene has been inactivated to facilitate analysis of the knocked-out gene’s activity and function
Molecular medicine adjective Referring to the inactivation of a specific gene or genes noun A lab organism—e.g., yeast or mouse—in which a specific gene is altered, inactivating it and creating a model for a particular disease; in knockouts, an extracellular signal is converted to a functional intracellular change
Sports medicine KO The vanquishing of an opponent in a combat sport by bringing the opponent to the mat or ground. In boxing, this is defined as when the boxer is knocked down and cannot get up by the referee’s count of 10. A technical knockout (TKO) is one in which the referee or ringside doctor determines that the fighter is unable to defend himself or has sustained a serious injury, or when the fighter’s handlers throw in the towel
Vox populi Bombshell A woman who is stunningly beautiful
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

knock·out

, knock-out (nok'owt)
A genetically engineered organism in which the genome has been altered by site-directed recombination so that a gene is deleted.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

knockout

see GENE DISRUPTION.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Najib then sought to draw Lim's son into the dispute, asking if the performance of the country's stock markets could be considered a 'knockout blow' to Finance Minister Lim Guan Eng.
The win on Sunday was Pacquiao's first knockout triumph since he scored his last stoppage almost 10 years back, when he halted Puerto Rican legend Miguel Cotto in the 12th round in 2009.
With his fans cheering him on in hope of another knockout, Lippe-Morrison connected with a hard right hook to Thomas' head just over a minute into the opening stanza, sending Thomas to the canvas.
This article contains spoilers from "The Voice" Season 7 (2014) Knockout Rounds-Part 3.
KNOCKOUT king Tommy McCarthy insists he feels no pressure to add to his canvas-thumping record.
They are ready-to-use in the "gold standard" 21-day monolayer Caco assay for studying efflux characteristics and so allows flexibility in the choice and trial of the efflux transporter knockout cell lines to optimize preclinical screening.
"I really want that 50th knockout. It is like a golden number," the Ukrainian said.
Recommendation L Kirakosyan towin by knockout 1pt 11-8 Stan James, Victor Chandler
With a grant from AIATSIS, I researched the social, cultural and (to a lesser extent) economic aspects of the annual New South Wales Aboriginal Rugby League Knockout competition (Norman 2006).
In week three he beat current leader Trevor Frost 3-1 in the 'A' knockout final despite Frost hitting two maximums.
Ultimate Knockouts Vol 5 packs a punch with a series of spectacular knockouts, including 29 matches and match highlights.
Both had fought twice and won by knockouts both times.