kinins


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Related to kinins: Prostaglandins, Cytokines

kinins

substances that cause vascular smooth-muscle relaxation, inducing vasodilatation and inflammation
References in periodicals archive ?
Kinins also cause airway wall edema, which can influence the relaxation of the airways after a contractile stimulus (Wagner 1997).
Increased airway kinin levels occur after exposure to a variety of noxious stimuli (Lauredo et al.
These data indicate that, as with other types of irritants, brevetoxin increases kinin levels in the airways and that this inflammatory mediator contributes to toxin-induced airway responses.
The enzyme exhibited the ability to release kinin causing visceral smooth muscle contraction.
Because there is a time gap between infection of nasal passages and the influx of kinins into tissues, he suspects that the viruses may be activating kinin production.
Using nasal discharges from 40 volunteers infected with rhinoviruses, the researchers found that kinin levels increased 20- to 80-fold in the two-thirds who developed symptoms.
Kinins are potent mediators of pain and vasodilation.
3) In vertebrates, clotting and inflammation have diverged into the specialized functions of the platelets, phagocytic cells (neutrophils and macrophages), and several plasma protein systems (procoagulant proteins, complement proteins, proteins of the kinin system).
15) Most of the effects of bradykinin are mediated through the endothelial B2 kinin receptor.
29) suggest that the release of kinin should still be considered the primary effect of hK1.
Kallikrein and kinin receptor expression in inflammation and cancer.