kinin


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kinin

 [ki´nin]
the generic term for any of the polypeptides related in amino acid sequence and physiological activity to bradykinin and kallidin, formed by kallikrein-mediated cleavage of kininogens. Kinins are plasma proteins that increase vascular permeability, interact with prostaglandins to cause pain and smooth muscle contraction and to increase the migration of white blood cells during the inflammatory process, and act as potent renal vasodilators to increase the renal excretion of sodium.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ki·nin

(kī'nin),
Polypeptide hormones that are released from diffuse stores and not from specialized tissue. they are rapidly inactivated at the site of release.
[G. kineō, to move, + -in]
Farlex Partner Medical Dictionary © Farlex 2012

kinin

(kī′nĭn)
n.
Any of various structurally related polypeptides, such as bradykinin, that act locally to induce vasodilation and contraction of smooth muscle.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ki·nin

(kī'nin)
One of a number of substances having pronounced physiologic effects. Some are polypeptides, formed in blood in various pathologic processes, which stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation.
[G. kineō, to move, + -in]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

kinin

One of a family of POLYPEPTIDES, released as a part of the inflammatory process, which increase the leakiness of small blood vessels and cause smooth muscle fibres to contract.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

kinin

the old name for CYTOKININ.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

ki·nin

(kī'nin)
Polypeptide hormones released from diffuse stores and not from specialized tissue, rapidly inactivated at the site of release.
[G. kineō, to move, + -in]
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Altered frequency of a promoter polymorphic allele of the kinin B1 receptor gene in inflammatory bowel disease.
As an important element of the kallikrein/kinin system (KKS), tissue kallikrein can cleave low-molecule kininogen into kinins (e.g., bradykinin and kallidin).
Scorpion (Buthus tamulus) venom toxicity on cardiopulmonary reflexes involves kinins via 5-HT3 receptor subtypes.
Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling.
Yates, "Hypertensive effect of tissue kallikrein in rostral ventrolateral medulla is mediated by brain kinins," Brain Research, vol.
An activation of the complement cascade or the kinin system may also be responsible for histamine release.
Kallikrein interference as an enzyme of kinin system which has a close relation with renin angiotensin system could increase glomerular membrane penetrability [5,17].
Olson, "Brady kinin inhibition of EGF- and PDGF-induced DNA synthesis in human fibroblasts, " The American Journal of Physiology--Cell Physiology, vol.
Skidgel, "Characterization of dual agonists for kinin [B.sub.1] and [B.sub.2] receptors and their biased activation of B2 receptors," Cellular Signalling, vol.
Itching can be caused by a number of physical stimulichanges in temperature, superficial touches, chemical- histamine, kinin, opioid peptides, vasoactive intestinal polypeptide (VIP), serotonin, prostaglandin F1, but also emotional factors.
The mechanism by which lignocaine prevents pain when applied prior to propofol injection is reported to be its local anaesthetic effect on the vein and its stabilisation of the kinin cascade (1).