kinin


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kinin

 [ki´nin]
the generic term for any of the polypeptides related in amino acid sequence and physiological activity to bradykinin and kallidin, formed by kallikrein-mediated cleavage of kininogens. Kinins are plasma proteins that increase vascular permeability, interact with prostaglandins to cause pain and smooth muscle contraction and to increase the migration of white blood cells during the inflammatory process, and act as potent renal vasodilators to increase the renal excretion of sodium.

ki·nin

(kī'nin),
Polypeptide hormones that are released from diffuse stores and not from specialized tissue. they are rapidly inactivated at the site of release.
[G. kineō, to move, + -in]

kinin

/ki·nin/ (ki´nin) any of a group of vasoactive straight-chain polypeptides formed by kallikrein-catalyzed cleavage of kininogens; causing vasodilation and also altering vascular permeability.

kinin

(kī′nĭn)
n.
Any of various structurally related polypeptides, such as bradykinin, that act locally to induce vasodilation and contraction of smooth muscle.

kinin

[kī′nin]
any of a group of polypeptides with varying physiological activity, such as contraction of visceral smooth muscle, vascular permeability, and vasodilation. Two principal kinins, bradykinin and lysylbradykinin, are formed in the blood from precursor kininogens by the action of kallikrein and kinases.

ki·nin

(kī'nin)
One of a number of substances having pronounced physiologic effects. Some are polypeptides, formed in blood in various pathologic processes, which stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation.
[G. kineō, to move, + -in]

kinin

One of a family of POLYPEPTIDES, released as a part of the inflammatory process, which increase the leakiness of small blood vessels and cause smooth muscle fibres to contract.

kinin

the old name for CYTOKININ.

ki·nin

(kī'nin)
Polypeptide hormones released from diffuse stores and not from specialized tissue, rapidly inactivated at the site of release.
[G. kineō, to move, + -in]

kinin

(kī´nin),
n a number of widely differing substances having pronounced and dramatic physiologic effects. Some are formed in blood by proteolysis secondary to some pathologic process. Kinins stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation. May be involved in periodontal disease.

kinin

any of a group of endogenous peptides that increase vascular permeability, elevate blood pressure, and induce smooth muscle contraction.

venom kinin
a peptide found in the venom of insects.
References in periodicals archive ?
Scorpion (Buthus tamulus) venom toxicity on cardiopulmonary reflexes involves kinins via 5-HT3 receptor subtypes.
Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.
Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling.
Kinins derived from kininogen produced by tissue kallikrein (TK) exert a broad spectrum of cellular functions via activation of the bradykinin B1 or B2 receptor (B1R or B2R, resp.
The first phase is mediated through the release of histamine, serotonin and kinins whereas the second phase is related to the release of prostaglandin and slow reacting substances which peak at 3h (Vinegar et al.
Then we clarified that it was extravasated more selectively in solid tumor as was a case observed by bacterial infected site where blue albumin was extravasated due to kinin generation.
Akut hemolitik transfuzyon reaksiyonu antijen--antikor reaksiyonu ile baslatilan; kompleman, koagulasyon, kinin sistemlerinin aktive edildigi bir durumdur.
Karvezide tablet, 4 yildir Endol kapsul 3x1, Kinin 200 mg tablet 1x1, 51 Arava tablet 1x1 ve Prednol 16 mg tablet 1x1/4, Nevofam 40 mg 1x1 kullaniyordu.
Biochemical properties of a bushmaster snake venom serine proteinase (LV-Ka) and its kinin releasing activity evaluated in rat mesenteric arterial rings.
Birn27 attributes the cause of pain to the presence and formation of kinin locally in the socket.
Inflammation is classified as acute or chronic depending on the type and duration of the antigen challenge and is mediated by some chemical substances such as histamine, serotonin, Slow Reacting Substances of Anaphylaxis (SRS-A) (leukotrienes), prostaglandin and some plasma enzyme systems such as the complement system, the clotting system, the fibrinolytic system and kinin system.