kinetoplast


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Related to kinetoplast: Kinetoplastida

kinetoplast

 [kĭ-ne´to-plast]
an accessory body found in many protozoa, primarily the Mastigophora; it contains DNA and replicates independently.

ki·ne·to·plast

(ki-nē'tō-plast, ki-net'ō-),
An intensely staining rod-shaped, diskoid, or spheric extranuclear DNA structure found in parasitic flagellates (family Trypanosomatidae) near the base of the flagellum, behind the blepharoplast, and often at right angles to the nucleus. Visible by light microscopy, electron micrographs reveal it as part of a single giant mitochondrion filling most of the cytoplasm of amastigote flagellates. Identifying kinetoplast as kDNA distinguishes it from nuclear DNA(nDNA). The kinetoplast divides independently, but with the basal body, before nuclear division. Kinetoplast formerly included parabasal body and blepharoplast in a locomotory apparatus but is now recognized as a distinct organelle of most trypanosomatids.
See also: parabasal body.
[kineto- + G. plastos, formed]

kinetoplast

/ki·ne·to·plast/ (ki-nēt´o-plast) a structure associated with the basal body in many protozoa, primarily the Mastigophora; it is rich in DNA and, like the basal body, it replicates independently.

kinetoplast

(kə-nĕt′ə-plăst′, -nē′tə-, kī-)
n.
A loop of DNA located in a large mitochondrion that lies near the base of the flagellum in certain protozoans.

ki·ne·to·plast

(ki-nē'tō-plast)
An intensely staining extranuclear DNA structure found in parasitic flagellates near the base of the flagellum. Electron micrographs show it to be part of a single giant mitochondrion filling most of the cytoplasm of amastigote flagellates.
See also: parabasal body
[kineto- + G. plastos, formed]

kinetoplast

see KINETOSOME.

kinetoplast

an accessory body found in many protozoa, primarily the Mastigophora; it contains DNA and replicates independently.
References in periodicals archive ?
Polymerase chain reaction amplification of Trypanosoma cruzi kinetoplast minicircle DNA isolated from whole blood lysates: diagnosis of chronic Chagas' disease.
The divergent region of the Leishmania tarentolae kinetoplast maxicircle DNA contains a diverse set of repetitive sequences.
Avila HA, Pereira JB, Thiemann O, de Paiva E, Degrave W, Morel CM and Simpson L: Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by polymerase chain reaction amplification of kinetoplast minicircle DNA: comparison with serology and xenodiagnosis.
Overall, 18 hybrids were eventually recovered, each showing a full set of chromosomes from each parent plus additional genetic material called kinetoplast DNA from one parent.
Some flagellates have a deoxyribonucleic acid (DNA) containing structure in the mitochondrion called a kinetoplast.
Stained specimens were often characterized by trypanomastigotes and epimastigotes with a large oval kinetoplast and a nucleus in the center of the body.
A simple protocol for the physical cleavage of Trypanosoma cruzi kinetoplast DNA present in blood samples and its use in polymerase chain reaction (PCR)-based diagnosis of Chagas disease.
Kinetoplast DNA signatures of Trypanosoma cruzi strains obtained directly from infected tissues.
cruzi kinetoplast and also nuclear DNA can be integrated into the host genome.
Sand flies and rodents were also collected from different endemic villages; none of the trapped rodent samples tested positive for leishmaniasis, but samples from sand flies from 2 endemic villages of North Waziristan (Razmak and Shewa) and 1 endemic village of South Waziristan (Sreykhoray) tested positive by kinetoplast DNA PCR.
The qPCR reactions were performed using the primers LEISH-1 (5 '-AACTTTTCTGGTCCTCCGGGTAG-3') and LEISH-2 (5'-ACCCCCAGTTTCCCGCC-3') and the FAM probe (5' -AAAAATGGGTGCAGAAAT-3' NFQ-MGB) that amplify the kinetoplast minicircle DNA of Leishmania spp.