killed vaccine


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killed vaccine

Etymology: ME, killen + L, vaccinus, of a cow
a vaccine prepared from dead microorganisms, generally used to provide immunization from organisms that are too virulent to be used in the living attenuated state. The immune system reacts to the presence of the pathogen in the same manner, whether the organism is alive or dead. However, immunity produced by a live, attenuated vaccine is usually more effective.

killed vaccine

A vaccine consisting of dead but antigenically active viruses or bacteria, which evokes production of protective antibodies without causing disease. Cf Live attenuated vaccine.

kill·ed vac·cine

(kild vak-sēn')
One made from dead microorganisms for immunization purposes.

killed vaccine

see dead vaccine.
References in periodicals archive ?
Presently, in Pakistan all killed vaccines are imported ones with high costs.
These results indicate that a combination of vaccines in which priming is done with a live attenuated vaccine at day 1, followed by boosters with a killed vaccine at day 10, and with a live vaccine at day 21 give the best protection.
The major advantage of killed vaccines is their safety; the disadvantages are that they often require multiple doses to elicit and sustain an effective immune response and that the immune response may be imbalanced, leading to subsequent potentiation of the disease (14,15).
The group is working with the Canadian company PerOs Systems Technologies to develop an oral delivery method for killed vaccines.
Vaccination program is only effective with strict biosecurity measures Live and killed vaccines are commonly used all over the world (Whithearils, 1996).
Killed vaccines are often combined with compounds called adjuvants, which increase the immune response of the patient and the protective immunity imparted by the vaccine.
Killed vaccines on the other hand usually require two doses, the first to prime the system and the second a short period later to produce the protective immunity with regular boosters.
iniae vaccine that appears to be superior to inactivated or killed vaccines.
Viruses that are used in killed vaccines are grown in embryonated eggs, purified, inactivated with formaldehyde, and usually then treated with a detergent to make the vaccine less pyrogenic.
Viruses in killed vaccines are grown in embryonated eggs, purified, inactivated with formaldehyde, and usually then treated with a detergent to make the vaccine less pyrogenic.
Immunizations with killed vaccines have not been shown to exacerbate SLE.

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