clock

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clock

(klŏk)
n.
1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
v.tr.
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

CLOCK

A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

clock

(klok)
A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.
Medical Dictionary, © 2009 Farlex and Partners

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm#120393201 Hope this helps.

More discussions about clock
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References in classic literature ?
"But," said the merchant, "How can I have killed your son?
I do not care to kill men with whom I have no quarrel."
thanks be to thee, great chief!" said those men of my people who sought to kill us.
"The First of the Tigers, standing stiffly to his kill, said.
As he spoke the Trojans drew close up, and Hector killed two men, both in one chariot, Menesthes and Anchialus, heroes well versed in war.
"I got them from the Wicked Witch of the East, when my house fell on her and killed her," she replied.
Yet had Knuckle- Bone forgotten that all the men of us had added our strength to keep the law among us, and him we killed, at the foot of his tree, and hung his body on a branch as a warning that the law was stronger than any man.
As soon as I had secured my two weak, rescued prisoners, and given them shelter, and a place to rest them upon, I began to think of making some provision for them; and the first thing I did, I ordered Friday to take a yearling goat, betwixt a kid and a goat, out of my particular flock, to be killed; when I cut off the hinder-quarter, and chopping it into small pieces, I set Friday to work to boiling and stewing, and made them a very good dish, I assure you, of flesh and broth; and as I cooked it without doors, for I made no fire within my inner wall, so I carried it all into the new tent, and having set a table there for them, I sat down, and ate my own dinner also with them, and, as well as I could, cheered them and encouraged them.
It swore every boy to stick to the band, and never tell any of the secrets; and if anybody done anything to any boy in the band, whichever boy was ordered to kill that person and his family must do it, and he mustn't eat and he mustn't sleep till he had killed them and hacked a cross in their breasts, which was the sign of the band.
"He is our brother in all but blood," Akela went on, "and ye would kill him here!
Say, shall I kill him, if I can get the better of him, or shall I bring him here that you may take your own revenge for all the many wrongs that he has done in your house?"
Eos then obtains of Zeus and bestows upon her son immortality; but Achilles routs the Trojans, and, rushing into the city with them, is killed by Paris and Apollo.