ketotifen fumarate


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ketotifen fumarate

An antihistamine that stabilizes mast cells, ↓ secretion of immune mediators
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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The salbutamol sulfate and ketotifen fumarate mixture is not yet official in any pharmacopoeia.
Pure drug samples of salbutamol sulfate and ketotifen fumarate were provided as a gift sample by East West Pharma, Uttarakhand, India.
Accurately weighed quantity of salbutamol sulfate (10 mg) and ketotifen fumarate (10 mg) was transferred to two separate 10 mL volumetric flasks, dissolved in little amount of methanol and diluted to the mark with methanol (stock solutions: 1000 [micro]g/mL of salbutamol sulfate and ketotifen fumarate).
Working standard solutions of salbutamol sulfate (100 [micro]g/ mL) and ketotifen fumarate (100 [micro]g/mL) were diluted appropriately with methanol to obtain solution containing salbutamol sulfate (10 [micro]g/mL) and ketotifen fumarate (10 [micro]g/mL).
Asignalat 257nm of first derivative spectrum was selected for quantification of salbutamol sulfate where no interference due to ketotifen fumarate was observed; similarly, a signal at 278 nm was selected for quantification of ketotifen fumarate, where salbutamol sulfate did not interfere with the estimation of ketotifen fumarate.
Calibration Curves for Salbutamol Sulfate and Ketotifen Fumarate. The standard solutions of salbutamol sulfate (100 [micro]g/mL) and ketotifen fumarate (100 [micro]g/mL) were used to prepare two different sets of working standard solutions of salbutamol sulfate (5-45 [micro]g/mL) and ketotifen fumarate (535 [micro]g/mL).
Marketed tablet formulations containing salbutamol sulfate (2 mg) and ketotifen fumarate (1 mg) were analyzed using this method.
The UV spectra of standard mixture (salbutamol sulfate (20 [micro]g/mL) + ketotifen fumarate (10 [micro]g/mL)) and sample solutions (tablet) were recorded between 200 and 400 nm and their absorbance measured.
The first was the control group; the second group was simply switched to a healthy diet; the third was given cromolyn or ketotifen fumarate; and the fourth was both given the drug and switched to a healthy diet.
However, the researchers tend to conduct more studies on the effect of cromolyn and ketotifen fumarate on obese and diabetic non-human primates.