ketotic hypoglycemia


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ketotic hypoglycemia

the most common form of childhood hypoglycemia after the neonatal period; usually presents between the ages of 18 months and 5 years and resolves spontaneously by late childhood. Episodes usually occur during minor illnesses and are characterized by inordinate sleepiness and decreased appetite; in susceptible children, fasting for more than 8-16 hours often precipitates symptoms; probably attributable to a defect in gluconeogenesis and inadequate glycogen stores.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Ketotic hypoglycemia is seen in older children with panhypopituitarism.
In the absence of evident clinical symptoms, the patients often exhibit near normal or moderately increased plasma concentrations of leucine, valine, and isoleucine, which are similar to the concentrations observed in secondary amino acid disturbances such as ketotic hypoglycemia, diabetes mellitus, starvation, and other catabolic states (5-10).
Plasma samples from patients with ketotic hypoglycemia were kindly provided by Dr.
Regarding the significance of increased plasma branched-chain amino acid concentrations for the diagnosis of MSUD, leucine, valine, and isoleucine should exceed ~400, 600, and 250 [micro]mol/L, respectively, to allow reliable differentiation of MSUD-induced increases from secondary disturbances of branched-chain amino acid metabolism that occur, e.g., in ketotic hypoglycemia (5, 6).