ketone body


Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to ketone body: keto acid, acetoacetate, thyrocervical trunk

ke·tone bod·y

one of a group of ketones that includes acetoacetate, its reduction product, β-hydroxybutyrate, and its decarboxylation product, acetone; high levels are found in tissues and body fluids in ketosis.

ketone body

n.
Any of three compounds, acetoacetic acid, acetone, and beta-hydroxybutyric acid, that are ketones or derivatives of ketones and are intermediate products of fatty acid metabolism. Ketone bodies accumulate in the blood and urine when fats are being used for energy instead of carbohydrates, as in individuals affected by starvation or uncontrolled diabetes mellitus. Also called acetone body.

ke·tone bod·y

(kē'tōn bod'ē)
One of a group of ketones that includes acetoacetic acid, β-hydroxybutyric acid, and acetone; high levels are found in tissues and body fluids in ketosis.
Synonym(s): acetone body.

ke·tone bod·y

(kē'tōn bod'ē)
One of a group of ketones that includes acetoacetate, its reduction product, β-hydroxybutyrate, and its decarboxylation product, acetone.
References in periodicals archive ?
Foster, "Regulation of hepatic fatty acid oxidation and ketone body production," Annual Review of Biochemistry, vol.
Arterial ketone body ratio in pediatric liver transplantation.
[2] Nonstandard abbreviations: PT, prothrombin time; 1CG, indocyanine green; AST, aspartate aminotransferase; ALT, alanine aminotransferase; PNF, primary nonfunction; DNF, delayed nonfunction; MEGX, monoethylglycinexylidide; OLT, orthotopic liver transplantation; and AKBR, arterial ketone body ratio.
The direct oral intake of ketone body salts or acid, as described in some case reports, may not be totally free of health risks.
Interpersonal variation of ketone body levels in humans is a well-known fact, a publication from 1958 determined a difference of 30 percent in healthy young men after fasting overnight [31].
Testing of a ketone body ester consisting of D-1,3butanediol and D-[beta]HB (3-hydroxybutyl-3-hydroxybutyrate) exhibited a concentration peak between 1,5 and 2.5 h into testing.
The excessive intake of ketone body salt or acid could have consequences for the acid-base balance.
Boukaftane et al., "Medical aspects of ketone body metabolism," Clinical and Investigative Medicine, vol.
Further elevated plasma and brain ketone body levels could also affect AD via a variety of other mechanisms including (1) the blockade of A[[beta].sub.1-42] (the toxic form of [beta]-amyloid) entry into neurons which can decrease oxidative stress and amyloid burden [59] and (2) neuroprotection against [beta]-amyloid toxicity possibly by decreasing ROS production and decreasing BACE1 expression, the rate-limiting enzyme in A[[beta].sub.1-42] production [60].
(1994) indicated that when cows received 613-919 g PG daily during the milking peak period, markedly reduced serum ketone body concentrations resulted.