ketoacidosis


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Related to ketoacidosis: ketosis, diabetic ketoacidosis, Alcoholic ketoacidosis

ketoacidosis

 [ke″to-as″ĭ-do´sis]
the accumulation of ketone bodies in the blood, which results in metabolic acidosis; it is often associated with uncontrolled diabetes mellitus. See also ketosis.

ke·to·ac·i·do·sis

(kē'tō-as'i-dō'sis),
Acidosis, as in diabetes or starvation, caused by the enhanced production of ketone bodies.

ketoacidosis

/ke·to·ac·i·do·sis/ (ke″to-as″ĭ-do´sis) acidosis accompanied by the accumulation of ketone bodies in the body tissues and fluids.
diabetic ketoacidosis  see under acidosis.

ketoacidosis

(kē′tō-ăs′ĭ-dō′sĭs)
n. pl. ketoaci·doses (-dō′sēz)
1. Metabolic acidosis caused by an abnormally high concentration of ketone bodies in the blood and body tissues.
2. This condition occurring as a complication of untreated or improperly controlled diabetes mellitus, especially type 1 diabetes, characterized by thirst, fatigue, a fruity odor on the breath, and other symptoms, and having the potential to progress to coma or death. Also called diabetic ketoacidosis.

ketoacidosis

[kē′tōas′idō′sis]
Etymology: Gk, keton, form of acetone; L, acidus, sour, osis, condition
acidosis accompanied by an accumulation of ketones in the body, resulting from extensive breakdown of fats because of faulty carbohydrate metabolism. It occurs primarily as a complication of diabetes mellitus and is characterized by a fruity odor of acetone on the breath, mental confusion, dyspnea, nausea, vomiting, dehydration, weight loss, and, if untreated, coma. Emergency treatment includes the administration of insulin and IV fluids and the evaluation and correction of electrolyte imbalance. Nasogastric intubation and bladder catheterization may be required if the patient is comatose. Before discharge of the patient from the hospital, the nurse carefully reviews the meal plan, activity, blood glucose and urine ketone monitoring, and insulin schedule prescribed, emphasizing to the patient that ketoacidosis may be life-threatening and is largely avoidable by strict adherence to the patient's diabetic regimen, monitoring, and appropriate action for illness or stress. See also diabetes mellitus, ketosis. ketoacidotic, adj.

ketoacidosis

Diabetic ketoacidosis, DKA A type of metabolic acidosis seen in poorly controlled DM, with 'starvation amidst plenty'; despite hyperglycemia, ↓ insulin makes the excess glucose unavailable to the cells, which rely on lipid metabolites–ketone bodies–for energy, due to incomplete lipid metabolism Clinical Systemic acidosis, ↓ cardiac contractility and vascular response to catecholamines with thready pulse, hypotension, poor organ perfusion and diabetic ketoacidosis may be the presenting sign in previously undiagnosed DM, accompanied by an acute abdomen and marked leukocytosis Lab Ketonuria, ketonemia, hyperglycemia, glycosuria, ↓ pH, ↓ bicarbonate, ↑ anion gap, hyperlipidemia. See Alcoholic ketoacidosis.

ke·to·ac·i·do·sis

(kē'tō-as-i-dō'sis)
Acidosis, as in diabetes mellitus or starvation, caused by the enhanced production of ketone bodies.

ketoacidosis

See KETOSIS.

Ketoacidosis

A condition due to starvation or uncontrolled Type I diabetes. Ketones are acid compounds that form in the blood when the body breaks down fats and proteins. Symptoms include abdominal pain, vomiting, rapid breathing, extreme tiredness, and drowsiness.

ketoacidosis

decrease in pH of body fluids due to accumulation of ketone bodies (beta-hydroxybutyric acid, acetoacetic acid and acetone), products of the metabolism of fat. A complication of diabetes, because of non-availability to the tissues of glucose; also occurs in starvation and (rarely) in alcohol misuse. See also acidosis.

ketoacidosis

acidosis due to overproduction of ketone (acetone) bodies; characteristic of uncontrolled diabetes mellitus; fatal if left untreated (see acetonuria; diabetic coma; ketoacidotic coma)

ketoacidosis (kēˈ·tō·a·si·dōˑ·sis),

n acidosis accompanied by an increase of ketones caused by widespread breakdown of fats as a result of inefficient carbohydrate metabolism. Typically a complication of diabetes mellitus. Characteristics include the presence of a noticeable fruity scent of acetone on a person's breath, dyspnea, mental confusion, nausea, weight loss, and dehydration.

ke·to·ac·i·do·sis

(kē'tō-as-i-dō'sis)
Acidosis, as in diabetes or starvation, caused by enhanced production of ketone bodies.

ketoacidosis (kē´tōas´idō´sis),

n a form of acidosis characterized by an increased accumulation of ketone bodies (acetoacetic acid, β-hydroxybutyric acid, acetone) in the blood (e.g., the acidosis of uncontrolled diabetes mellitus).

ketoacidosis

the accumulation of ketone bodies in the blood which results in metabolic acidosis. See also ketosis.

diabetic ketoacidosis
an overproduction and underutilization of ketone bodies in the diabetic results in ketosis. Ketonemia and ketonuria with accompanying loss of Na+ and K+, leads to a base deficit and acidosis.
References in periodicals archive ?
Ketoacidosis is a serious illness and can lead to hospitalization.
If ketoacidosis has already supervened, then the symptoms can include vomiting, deep sighing respiration, reduced conscious level, and abdominal pain.
I would like to share the 8 signs your child may have Type I Diabetes (Bendall, 8/2010): Unquenchable thirst, frequent urination, weight loss, lack of energy, intense hunger, changes in appetite, yeast infection, and diabetic ketoacidosis.
Even a single case of diabetic ketoacidosis developing in hospital is unacceptable because it suggests that insulin has been withheld from that person for some time .
The most serious complication of both HHS and diabetic ketoacidosis are cerebral edema and acute respiratory distress syndrome (7).
Untreated, Type 1 diabetes can result in serious health problems such as diabetic ketoacidosis, which can lead to a potentially fatal coma.
This is one of the reasons why a quarter of children with Type 1 diabetes are only diagnosed once they are already seriously ill with diabetic ketoacidosis, a life-threatening condition that needs immediate treatment in hospital.
He was on the verge of having diabetic ketoacidosis because he was not getting enough insulin into his system to help lower his blood sugar.
Linagliptin/metformin HCl are not for the treatment of Type 1 Diabetes or diabetic ketoacidosis (increased ketones in the blood or urine).
Additionally, the high [beta]-hydroxybutyrate concentration is indicative of ketoacidosis; however, because this patient's plasma was mildly hypoglycemic and because no history of type I diabetes could be ascertained, diabetic ketoacidosis (DKA) [2] was considered highly improbable (2).
If the patients, suffering from low or high blood sugar levels, do not break the fast, it can lead to diabetes ketoacidosis or state of comatose condition," Amal further said.
On the other hand, a condition called Diabetic Ketoacidosis can occur in people with type-1 diabetes when there is no insulin in the body.