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Acidosis, as in diabetes or starvation, caused by the enhanced production of ketone bodies.
n. pl. ketoaci·doses (-dō′sēz)
1. Metabolic acidosis caused by an abnormally high concentration of ketone bodies in the blood and body tissues.
2. This condition occurring as a complication of untreated or improperly controlled diabetes mellitus, especially type 1 diabetes, characterized by thirst, fatigue, a fruity odor on the breath, and other symptoms, and having the potential to progress to coma or death. Also called diabetic ketoacidosis.
ketoacidosisDiabetic ketoacidosis, DKA A type of metabolic acidosis seen in poorly controlled DM, with 'starvation amidst plenty'; despite hyperglycemia, ↓ insulin makes the excess glucose unavailable to the cells, which rely on lipid metabolites–ketone bodies–for energy, due to incomplete lipid metabolism Clinical Systemic acidosis, ↓ cardiac contractility and vascular response to catecholamines with thready pulse, hypotension, poor organ perfusion and diabetic ketoacidosis may be the presenting sign in previously undiagnosed DM, accompanied by an acute abdomen and marked leukocytosis Lab Ketonuria, ketonemia, hyperglycemia, glycosuria, ↓ pH, ↓ bicarbonate, ↑ anion gap, hyperlipidemia. See Alcoholic ketoacidosis.
Acidosis, as in diabetes mellitus or starvation, caused by the enhanced production of ketone bodies.
A condition due to starvation or uncontrolled Type I diabetes. Ketones are acid compounds that form in the blood when the body breaks down fats and proteins. Symptoms include abdominal pain, vomiting, rapid breathing, extreme tiredness, and drowsiness.
Acidosis, as in diabetes or starvation, caused by enhanced production of ketone bodies.