ketamine


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ketamine

 [ke´tah-mēn]
a nonbarbiturate anesthetic related to phencyclidine, administered intravenously or intramuscularly to produce dissociative anesthesia. Approximately 12 per cent of patients experience emergence reactions, which can include frightening hallucinations and dreams.

ket·a·mine

(kēt'ă-mēn),
A parenterally administered anesthetic that produces catatonia, profound analgesia, increased sympathetic activity, and little relaxation of skeletal muscles; side effects include sialorrhea and occasional pronounced dysphoria, especially in adults; chemically related to phencyclidine (PCP), it can produce hallucinations.

ketamine

/keta·mine/ (ke´tah-mēn) a rapid-acting general anesthetic, used as the hydrochloride salt.

ketamine

(kē′tə-mēn′)
n.
A general anesthetic given intravenously or intramuscularly, used especially for minor surgical procedures in which muscle relaxation is not required, and used illegally as a recreational drug.
A surgical anaesthetic withdrawn from the market due to disorientation and violent behaviour that occurred when patients regained consciousness; on the club scene, ketamine is in liquid form or a white powder snorted or smoked with marijuana or tobacco products
Pharmacologic effects Dissociative anaesthesia, CNS stimulant, hallucinations, visual distortion, a loss of senses, sense of time, and identity for 30 minutes to 2 hours, delirium, amnesia, impaired motor function, hypertension, depression, recurrent flashbacks, potentially fatal respiratory problems

ketamine

Substance abuse A surgical anesthetic withdrawn from the market due to disorientation and violent behavior that occurred when Pts regained consciousness; on the club scene, ketamine is in liquid form or a white powder snorted or smoked with marijuana or tobacco products Pharmacologic effects Dissociative anesthesia, CNS stimulant, hallucinations. visual distortion, a loss of senses, sense of time, and orientation for 30 mins to 2 hr, delirium, amnesia, impaired motor function, HTN, depression, recurrent flashbacks, potentially fatal respiratory problems

ketamine

A drug used to produce insensitivity to pain, mental and emotional dissociation and lack of awareness so that surgical procedures can be carried out on a conscious patient. It is related to PHENCYCLIDINE. The drug is on the WHO official list.A brand name is Ketalar.

ket·a·mine

(kēt'ă-mēn)
A parenterally administered anesthetic that produces catatonia, profound analgesia, increased sympathetic activity, and little relaxation of skeletal muscles; side-effects include sialorrhea and occasional pronounced dysphoria.

ketamine,

n a parenterally administered anesthetic that produces catatonia, profound analgesia, increased sympathetic activity, and little relaxation of skeletal muscles.
References in periodicals archive ?
This report is the second independent, peer-reviewed confirmation of the potential value of D-cycloserine in extending the effect of Ketamine in the treatment of acute depression.
Detection of ketamine and its metabolites in urine by ultra high pressure liquid chromatography-tandem mass spectrometry.
Ketamine was given to 21 patients at a median dose of 70 mg IV or 250 mg IM.
Ketamine bladder syndrome: an important differential diagnosis when assessing a patient with persistent lower urinary tract symptoms.
senior investigator with the Intramural Research Program at the National Institute on Aging, Baltimore said that the clinical use of ketamine therapy for depression is limited because the drug is administered intravenously and may produce adverse effects such as hallucinations and sedation to the point of anesthesia.
Depression also did not differ significantly, although there were two women (5%) who reported being depressed at 1 year in the saline group compared with none in the ketamine group.
Ketamine, which has been employed as a human and animal anesthetic, has been found to act in the human brain by blocking the N-methyl-D-aspartic acid (NMDA) receptor, which receives nerve signals carried by the neurotransmitter glutamate.
Comparative evaluation of midazolam and ketamine with midazolam alone as oral premedication.
Understanding how ketamine triggers antidepressant effects could open up a whole new way to think about treating depression, he says, perhaps by developing drugs that have the same net effect as ketamine.
3, Webster, is charged with two counts of possession of opium and ketamine, two counts of possession of opium and ketamine with intent to distribute, three counts possession of
US medical researchers believe the popular, but illegal, party drug ketamine could provide quick relief to severely depressed patients, especially in the early days of a crisis.
These enforcement activities yielded several particularly significant seizures, including the seizure of 847 kilograms of ketamine in January, the largest ketamine seizure in Taiwan's history.