keratolysis


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keratolysis

 [ker″ah-tol´ĭ-sis]
loosening or separation of the horny layer of the epidermis.
pitted keratolysis (keratolysis planta´re sulca´tum) a tropical disease marked by thickening and deep fissuring of the skin of the soles, occurring during the rainy season.

ker·a·tol·y·sis

(ker'ă-tol'i-sis), Avoid the mispronunciation keratoly'sis.
1. Separation or loosening of the horny layer of the epidermis.
2. Specifically, a disease characterized by a shedding of the epidermis recurring at more or less regular intervals. Synonym(s): deciduous skin
[kerato- + G. lysis, loosening]

keratolysis

(kĕr′ə-tō-lī′sĭs)
n. pl. keratoly·ses (-sēz)
1. The separation or loosening of the horny layer of the epidermis.
2. A skin disease characterized by a periodic shedding of the epidermis.

ker′a·to·lyt′ic (-lĭt′ĭk) adj.

ker·a·tol·y·sis

(ker'ă-tol'i-sis)
1. Separation or loosening of the horny layer of the epidermis.
2. A disease characterized by a shedding of the epidermis recurring at more or less regular intervals.
[kerato- + G. lysis, loosening]

keratolysis

Peeling off and shedding of the outer layer of the skin (the epidermis) or of the horny layer of the epidermis from the lower, still-living zone. In some cases affecting the soles of the feet, the condition is caused by the organisms Acinomyces or Corynebacterium .

keratolysis

A severe corneal disorder in which the corneal stroma melts, which may result in descemetocele or even perforation. It is believed to be due to an altered epithelial barrier, which results in inflammatory mediators entering the stroma. The condition may occur as a complication of necrotizing scleritis or a severe inflammation of the peripheral cornea, especially in patients with a severe dry eye.

ker·a·tol·y·sis

(ker'ă-tol'i-sis) Avoid the mispronunciation keratoly'sis.
1. Separation or loosening of horny epidermal layer.
2. Specifically, disease characterized by shedding of epidermis recurring at more or less regular intervals.
[kerato- + G. lysis, loosening]
References in periodicals archive ?
Isolation of Kytococcus sedentarius from a case of pitted keratolysis. Ege Tip Dergisi 2005;44:117-8.
Ultrastructure of pitted keratolysis. Int J Dermatol 2000;39:698-709.
Pitted keratolysis (PK), also known as keratolysis plantare sulcatum, is a skin disorder characterized by pits and collarettes from bacterial infection.
The differential diagnosis for PK may include the following, especially when the soles are involved: candidal infections, basal cell nevus syndrome, and keratolysis exfoliativa.
Among the miscellaneous dermatoses, Keratinisation disorders were seen in 15 patients (5%), Corns were seen in 12 patients (4%), Trophic ulcers were seen in 15 patients (5%), Keloid in 6 patients (2%) and Keratolysis exfoliativa in 9 patients (3%).
The condition predisposes to or worsens diseases like fungal infections, contact dermatitis, pompholyx and pitted keratolysis.
The differential diagnosis includes dry skin, pitted keratolysis, erythrasma, and contact dermatitis.
Tinea pedis infections also lack the well-demarcated erosions, or pits, of pitted keratolysis. Evidence of concurrent onychomycosis should increase the suspicion that tinea pedis is the correct diagnosis.
Shelley et al in 1982 described the coexistence of erythrasma with pitted keratolysis and trichomycosis axillaris.
Less common non-infectious dermatoses included Addisonian pigmentation, psoriasis, lichen planus, vitiligo, asteatotic eczema, phytodermatitis, keratolysis exfoliativa, miliaria pustulosa, erythema nodosum, neurofibromatosis and erythroderma.
RESULTS: Pyodermas clinical types (7) incidence--Of the 100 cases studied Impetigo 30% was the most commonest clinical type followed by Folliculitis (22%), Furunculosis (10%), Ecthyma (6%), Infected scabies (5%), Sycosisbarbae (5%), Erythrasma (5%), Cellulitis (3%), Infectious Eczematous Dermatitis (3%), Paronychia (3%), Carbuncle (2%), Periportis (2%), Infected wound (2%), Job's syndrome (1%), Pitted keratolysis (1%).
Three patients had Acrocordon and one each had Lichen Simplex Chronicus, Milia, Acne, Pyogenic Granuloma, Keratolysis Exfoliativa, Vitiligo, Arteriovenous (AV) Fistula Dermatitis, Fixed Drug Eruption, Gynecomastia, Non Palpable Purpura, Periorbital Oedema And Traumatic Leucoderma.