keratohyaline

keratohyaline

/ker·a·to·hy·a·line/ (-hi´ah-līn)
1. both horny and hyaline.
2. pertaining to keratohyalin or to the keratohyalin granules or the stratum granulosum of the epidermis.
References in periodicals archive ?
Perhaps abnormalities in keratin or the keratohyaline granules and/or modifications of the intercellular milieu induce changes that make epithelia look white.
Cytology of these tumors constituted large squamous cells with keratohyaline granules.
Vacuolization of cells with central nucleus, keratohyaline granules, blue gray cytoplasm (KOILOCYTES).
Since true leuconychia is thought to be due to abnormal matrix keratinization, with persistent parakeratosis and keratohyaline granules in the nail plate, so parakeratosis and dissociation of the keratin bundles may play a role in the modification of the solar light reflection by the ungual plates2.
Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules.
20) Two types of KFAP's can be distinguished based on the structures to which they contribute; the KFAP's such as loricrin and involucrin that are stored in a subset of keratohyaline granules form the subcytolemmal cornified cell envelope and the KFAP's that are stored in another subset of keratohyaline granules that combine with keratin filaments to form the filament matrix complex stabilizing the cytoskeleton of cornifying keratinocytes.
decreased thickness of the stratum corneum, decreased number and size of keratohyaline granules, and decreased amount of filaggrin.
The tubular epithelium is made up of four well-defined layers: a) a germinative layer where cell division occurs and consisting of one or two strata of flat or cuboidal cells with a basophilic cytoplasm and dark nucleus, b) an intermediate layer consisting of 1-5 strata of polygonal cells with a basophilic cytoplasm, c) a secretory layer formed by 1-10 layers of voluminous polygonal cells with secretory granules and, d) a degenerative layer characterized by cells with pycnotic nuclei and keratohyaline granules in the cytoplasm.
Fine needle aspiration cytology was performed which didn't reveal presence of cyst, abscess or haematoma but showed presence of numerous small cluster of cells, anisocytosis, anisokaryosis, multinucleated, prominent nucleoli, keratohyaline granules and emperipoles with irregular shape suggestive of tumor.
On permanent section, the absence of dry flaky keratin and a keratohyaline layer exclude epidermoid cyst, and the absence of calcification and wet keratin negate adamantinomatous craniopharyngioma (Figure 8, c and d).
Sybert VP, Dale BA, Holbrook KA: Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules.