keratoglobus


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megalocornea

 [meg″ah-lo-kor´ne-ah]
a developmental anomaly of the cornea, which is of abnormal size at birth and continues to grow, sometimes reaching a diameter of 14 or 15 mm in the adult.

ker·a·to·glo·bus

(ker'ă-tō-glō'bŭs),
Congenital anomaly consisting of an enlarged anterior segment of the eye.
[kerato- + L. globus, ball]

megalocornea

An X-linked recessive, nonprogressive enlargement of the cornea to 13 mm or greater, which is present at birth; 90% of cases occur in males. The cornea and the limbus are enlarged but histologically normal. Associated findings include anterior megalophthalmos, enlarged ciliary ring with zonular stretching (leading to phacodonesis), ectopia lentis, iridodonesis, iris stromal hypoplasia, posterior embryotoxon, transillumination defects, Krukenberg spindles, trabecular meshwork pigmentation, posterior embryotoxon, Rieger anomaly, goniodysgenesis and cataracts. It is usually isolated, but may be associated with other ocular and systemic findings.

keratoglobus

A condition in which the cornea bulges abnormally causing MYOPIA and distorted vision.

keratoglobus

A rare, usually bilateral, protrusion of the cornea with general thinning, especially in the periphery. The condition is usually present at birth and generally does not progress. Some cases may be acquired perhaps as the end-stage of keratoconus. The diameter of the cornea is normal or slightly increased and the intraocular pressure is normal as the condition is not associated with congenital glaucoma. Complications include perforation after minor trauma and corneal hydrops. It is sometimes associated with Leber's congenital amaurosis, Ehlers-Danlos syndrome and blue sclera. Syn. macrocornea. See megalocornea.
References in periodicals archive ?
Global keratoconus treatment market has been segmented on the basis of type which comprises of forme fruste keratoconus, corneal hydrops, keratoglobus, pellucid marginal degeneration, posterior keratoconus, and others.
Keratoconus, Keratoglobus, Pellucid marginal degeneration, keratectasia following refractive surgery, Stromal opacities/scars sparing Descemet's membrane and Corneal dystrophies involving anterior/deep stroma.
Introducing the 28-lens Zenlens DX set, B+L highlighted that scleral lenses are an invaluable tool for correcting issues such as keratoconus and keratoglobus.
Elder, "Leber congenital amaurosis and its association with keratoconus and keratoglobus," Journal of Pediatric Ophthalmology and Strabismus, vol.
Patients with serious corneal scarring, pellucid marginal degeneration, keratoglobus, previous ocular surgery, and any other significant ophthalmic pathology other than keratoconus were excluded from the study.
Keratoconus is a degenerative corneal condition and forms a subtype in a group of conditions termed ectasias, derived from the Greek meaning 'dilation or distention of a tubular structure/ the other conditions being pellucid marginal degeneration and keratoglobus. Ectasias cause distortion in the corneal shape via a weakness in the bonds between the tubular-like configuration of the stromal collagen fibres.
Other conditions causing cloudy cornea with these breaks (see Figure 2) include keratoglobus and congenital glaucoma, which can be ruled out by noting corneal measurements, axial length, intraocular pressure and optic disc appearance.
Tomography can also be used to identify corneal changes in keratoglobus (see Figure 5).
These lenses are indicated for post refractive surgery, pellucid marginal degeneration, keratoglobus, Stevens-Johnson syndrome, post-trauma, ocular surface disease or when standard corneal lenses fail to centre adequately.
Keratoglobus may present with stable vision or bilateral visual impairment, and diffuse corneal thinning.
Scleral lenses are used for people with irregular corneas as a result of conditions such as keratoconus and keratoglobus, as well as following corneal transplant, traumatic injury and refractive surgery.
The primary indications for the Rose K2 XL lens are keratoconus, Pellucid Marginal Degeneration (PMD), keratoglobus and post surgical use, but it can be used on any irregular corneal condition, which cannot be successfully fitted within the limbus.