keratocystic odontogenic tumour


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keratocystic odontogenic tumour

A benign cystic lesion of the jaw—75% in mandible, 90% behind canines—which arises in the dental lamina, often associated with impacted teeth; average age, 41 years; male:female ratio, 2:1. If multiple tumours are seen, basal cell nevus syndrome (a condition accompanied by basal cell carcinoma, ovarian fibroma, palmar pits, and medulloblastoma) should be excluded.

Management
KCOTs notoriously recur; initial surgery should include a generous margin and a rim of uninvolved bone.
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References in periodicals archive ?
A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities.
Marsupialisation for keratocystic odontogenic tumours in the mandible: longitudinal image analysis of tumour size using 3D visualised CT scans.
In 2005 the parakeratinized cysts were redefined and renamed as keratocystic odontogenic tumour because of its higher mitotic activity, the orthkeratinized type becomes part of the odontogenic cysts.
Correlation between imaging features and epithelial cell proliferation in keratocystic odontogenic tumour.
Keratocystic odontogenic tumour in a hong kong community: The clinical and radiological features.
The keratocystic odontogenic tumour (KCOT) was first described by Philipsen in 19561 and its attributes were outlined by Pindborg and Hansen.
Study Design: A cross sectional study conducted on previously diagnosed cases of ameloblastoma and Keratocystic odontogenic tumour.
b) Carcinomas arising from keratocystic odontogenic tumour (odontogenic keratocyst).
1) This lesion was recently renamed as Keratocystic Odontogenic Tumour (KCOT) and reclassified as an Odontogenic neoplasm in the World Health Organization's 2005 edition of its histological classification of odontogenic tumours.
1 The odontogenic keratocyst (OKC) is now designated by the World Health Organization (WHO) as a keratocystic odontogenic tumour (KCOT) and is defined as "a benign unior multicystic, intraosseous tumour of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium and potential for aggressive, infiltrative behaviour.
2 With the new World Health Organization classification considering the odontogenic keratocyst as a neoplasm and renaming it as keratocystic odontogenic tumour (KCOT) it becomes imperative that both clinicians and pathologists alike possess a thorough knowledge of the differences between the more aggressive KCOT and the less aggressive OOC so that patients receive the most appropriate treatment.
Keratocystic odontogenic tumours are known for their peculiar behaviour, varied origin, debated development, unique tendency to recur and due to propensity of KCOT's to grow within medullary bone they have the potential to become extremely large without causing any clinical signs & symptoms.