keratin


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keratin

 [ker´ah-tin]
a scleroprotein that is the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of the enamel of the teeth. Its solution is sometimes used in coating pills when the latter are desired to pass through the stomach unchanged.

ker·a·tin

(ker'ă-tin),
Collective name for a group of proteins that form the intermediate filaments in epithelial cells. Keratins have a molecular weight between 40 kD and 68 kD and are separated one from another by electrophoresis and isoelectric focusing; thus separated, they are sequentially numbered from 1-20, and also subdivided into low, intermediate, and high molecular weight proteins. According to their isoelectric mobility they are either acidic or basic. In general, each acidic keratin protein has its basic equivalent with which it is paired to form the intermediate filaments; some keratin proteins, however, occur unpaired. Various epithelial cells contain different keratin proteins, in a tissue-specific manner. Antibodies to keratin proteins are widely used for histologic typing of tumors, and are especially useful for distinguishing carcinomas from sarcomas, lymphomas, and melanomas.
Synonym(s): ceratin, cytokeratin
[G. keras (kerat-), horn, + -in]

keratin

(kĕr′ə-tĭn)
n.
1. Any of a class of filamentous proteins that are abundant in the cytoskeleton of vertebrate epithelial cells and are the main constituents of the outer layer of skin and tough epidermal structures such as hair, nails, hooves, feathers, and claws.
2. Material composed principally of keratin proteins.

ke·rat′i·nous (kə-răt′n-əs) adj.

ker·a·tin

(ker'ă-tin)
A scleroprotein or albuminoid present in hair and nails; it contains a relatively large amount of sulfur, is insoluble in gastric juice, and is sometimes used for coating tablets that are intended to be dissolved only in the intestine.
Synonym(s): cytokeratin.
[G. keras (kerat-), horn, + -in]

keratin

A hard protein (scleroprotein) of cylindrical, helical molecular form occurring in horny tissue such as hair and nails and in the outer layers of the skin. Hair and nails consist almost wholly of keratin. Keratins are insoluble and cannot generally be split by PROTEOLYTIC enzymes.

keratin

a hard, fibrous, sulphur-containing protein with an alpha-helix structure, found in the epidermis of vertebrates, mainly in the outermost layers of skin. Keratin can have several forms: in scales, feathers, hooves, horns, claws and nails it is hard, while wool and hair are made up of a soft and flexible form.

Keratin

A tough, nonwater-soluble protein found in the nails, hair, and the outermost layer of skin. Human hair is made up largely of keratin.

ker·a·tin

(ker'ă-tin)
Collective name for a group of proteins that form intermediate filaments in epithelial cells. Keratins have a molecular weight of 40-68 kD and are either acidic or basic. Antibodies to keratin proteins are widely used for histologic typing of tumors and are especially useful for distinguishing carcinomas from sarcomas, lymphomas, and melanomas.
[G. keras (kerat-), horn, + -in]

Patient discussion about keratin

Q. skins does excrete oil and keratin what exactly is the whitish cape up that you can squeeze out from underskin

A. It sounds like you refer to sebum, an oily substance secreted by (how surprising :) ) sebaceus glands attached to the hair root. It's important for the skin, although abnormal secretion of it may cause diseases such as acne.

You may read more here:
http://en.wikipedia.org/wiki/Sebum#Sebum

More discussions about keratin
References in periodicals archive ?
The leading players operating in the Keratin market are also studied in the report to provide readers with a comprehensive overview of the competitive landscape in the market.
This qualitative comparison is supported by the consideration of the chemical similarity between keratin and Nylon 6.6, as both of them are polyamides.
As keratin is a defiant protein, its degradation demands such proteases that can actively recycle the feather waste [21].
This protein band may be involved in the degradation of feathers (keratin).
Taken together, these results highlight the biocompatibility, suitability and ease of using keratin coated surfaces for neonatal murine cardiomyocyte culture to study cardiac hypertrophy in vitro (6) and also the emphasize the importance of topography in assessing cardiac function.
We suggested that the size and depth of pores affected by diffusion of alginate arranged stand between or adjacent keratin molecule.
Our previous work has shown that Hcy, bound by a disulfide or an amide bond, is a component of human hair keratin [18].
The keratin powders were dissolved in a carbonate bicarbonate buffer (pH 9.6) solution that was formulated at concentrations of 1,000 [micro]g/mL, 100 [micro]g/mL, 10 [micro]g/mL, and 1 [micro]g/mL.
* Keratin, a structural component of hair, nails, and the outer layer of skin,
Keratin Oil, Fish Oil Omega-3, and Snake Oil are available in convenient packs of 400ml at SR 12 ($3.2) and 200 ml at SR7.
Notably, inherited keratin mutations causing type 2 pachyonychia congenita can produce EVHC along with a characteristic nail dystrophy, focal palmoplantar keratoderma, follicular keratosis, and multiple steatocysts.
'All these mutations target the initiation codon of methionine." As previously reported in EBS, immunostaining for keratin 14 is positive, outlining areas of cleavage within the basal cell layer of the skin.