CALCA

(redirected from katacalcin)

CALCA

A gene on chromosome 11p15.2 that encodes peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin, by tissue-specific alternative RNA splicing of gene transcripts and cleavage of inactive precursor peptides. Calcitonin regulates calcium and phosphorus metabolism; calcitonin gene-related peptide is a vasodilator; katacalcin is a calcium-lowering peptide.
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References in periodicals archive ?
C cells of thyroid, pulmonary and pancreatic tissues and it is enzymatically cleaved into (immature) katacalcin, calcitonin, and N-terminal region.
For the PCT assay, tubes were coated with a monoclonal antibody specific for the katacalcin part of PCT.