karyopyknotic index

kar·y·o·pyk·not·ic in·dex

an index used to monitor the hormonal status of the patient as reflected by exfoliated vaginal cells and their morphology; an expression of the percentage of intermediate and superficial cells from squamous cells of vaginal epithelium which have pyknotic nuclei.
References in periodicals archive ?
Other secondary measures included urogenital and ophthalmic symptoms, serum FSH, and karyopyknotic index. Patients were assessed at week 2 (screening), week 0 (baseline), and weeks 4, 8, and 12.