karyopyknosis


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Related to karyopyknosis: pycnotic, caseous necrosis

karyopyknosis

 [kar″e-o-pik-no´sis]
shrinkage of a cell nucleus, with condensation of the chromatin. adj., adj karyopyknot´ic.

kar·y·o·pyk·no·sis

(kar'ē-ō-pik-nō'sis),
cytologic characteristics of the nucleus of a cell that is in the process of programmed or induced cell death.
[karyo- + G. pyknos, thick, crowded, + -osis, condition]

kar·y·o·pyk·no·sis

(kar'ē-ō-pik-nō'sis)
Cytologic characteristics of the superficial or cornified cells of stratified squamous epithelium in which there is shrinkage of the nuclei and condensation of the chromatin into structureless masses.
[karyo- + G. pyknos, thick, crowded, + -osis, condition]
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2B) whereby its chromatin is distributed irregularly throughout the cytoplasm), karyopyknosis, nuclear vacuolization (Fig.
Karyorrhexis (double black arrows); Karyopyknosis in hepatocytes (green arrow); nuclear vacuolization (red arrow) and cytoplasmic degeneration (blue arrows).
After exposure of neurons to OGD 2 h and RP 12 h at 37 [degrees]C, microscopy revealed the destruction of neurons, OGD/RP-induced neuronal loss and progressive degeneration, which were characterized by karyopyknosis or karyolysis and shortage of dendrite trees.
Caption: Figure 1: Hematoxylin and eosin (HE) staining of representative sections of hippocampal CA1 region under a 400x light microscopy (scale bar = 25 [micro]m); the karyopyknosis in the model group was marked with arrows.
There were karyopyknosis, chromatin agglutination and apoptosis bodies under transmission electron microscope (TEM) when HUVECs were exposed to taspine at different concentrations.
Administration of C[Cl.sub.4] for seven weeks caused damage to the hepatic lobular structure and resulted in hepatocyte disorder, karyopyknosis, and interstitial fiber hyperplasia (Figures 4(b) and 4(e)).
Rat liver pathological observation is shown in Figure 5; compared with the control group (a), PMR group (b), CYP1A2 inhibitor control group (c), and CYP2E1 inhibitor group (d), CYP1A2 inhibitor + PMR group (e) showed hepatic sinusoid moderate expansion and congestion in the portal tract with some cell karyopyknosis that is an early stage of apoptosis, while CYP2E1 inhibitor + PMR group (f) showed cytoplasmic hydropic change in hepatocytes and hepatic sinusoid moderate expansion in the portal tract.
H-E staining revealed normal structure in neurons and the arteriole wall in WKY rats but remodeling and hyaline degeneration in the arteriole wall (Figures 1(a)-1(d)) and regional ischemic neurodegeneration, edema, and neuron karyopyknosis (Figures 1(e)-1(h)) in SHRs, which regularly expanded to the basal ganglia and the neocortex.