Within one section of kidney, very rare tubular epithelial cells of the medullary cone displayed
karyomegaly with large, 13-[micro]m, glassy, basophilic, intranuclear, viral inclusion bodies.
25 He observed
karyomegaly in the PCTs of the frog which was most marked in the 10-day treatment group.
In the four high-grade tumors with a low mitotic index,
karyomegaly (n=3) (Figure 1b), bizarre nuclei (n=1) and multinucleated cells (n=1) were seen.
These findings were correlated with the amelioration of CSP-induced tubular necrosis, degeneration,
karyomegaly, and tubular dilatation [65].
The bone marrow also showed similar cells, with
karyomegaly, dense chromatin, and coalescing vacuoles which were Periodic Acid Schiff (PAS) negative.
This
karyomegaly was zonal, being prominent near the central veins.
